Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | VCP | P55072 | 2/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | RHOA | P61586 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1066989 | 0.78 | APP (0.54) | TDP1CES1POLBMAPK1CA1 | |
| SCHEMBL3300911 | 0.75 | NPC1 (0.58) | TDP1VCPNAMPTCES1RHOA | |
| SCHEMBL3300908 | 0.75 | NPC1 (0.58) | TDP1VCPNAMPTCES1RHOA | |
| SCHEMBL28415746 | 0.75 | APP (0.50) | CES1SLC6A3CA1CA2MAPT | |
| Hydrochloric Acid SCHEMBL9347478 | 0.74 | NPC1 (0.57) | TDP1VCPNAMPTCES1RHOA | |
| Hydrochloric Acid SCHEMBL9347470 | 0.74 | NPC1 (0.57) | TDP1VCPNAMPTCES1RHOA | |
| SCHEMBL3529113 | 0.73 | MAPT (0.48) | SLC6A3CA1CA2MAPTALDH1A1 | |
| SCHEMBL27881 | 0.73 | MAPT (0.70) | TDP1POLBRHOAMAPTALDH1A1 | |
| Bicarbonate SCHEMBL1562172 | 0.72 | MAPK1 (0.68) | TDP1CES1POLBMAPK1CES2 | |
| Bicarbonate SCHEMBL27200925 | 0.72 | MAPK1 (0.68) | TDP1CES1POLBMAPK1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6875764-B1 | Urea and thiourea compounds useful for treatment of coccidiosis | NEW PHARMA RESEARCH SWEDEN AB (SE) | 2005-04-05 | — | — | US | disclosed |