SCHEMBL6297930

SCHEMBL6297930

CC1=NCCCC1c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
IGF1R P08069 1/20 0.37
ALOX15 P16050 1/20 0.37
TP53 P04637 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
CHRNB2 P17787 1/20 0.35
CHRNB4 P30926 1/20 0.35
CHRNA3 P32297 1/20 0.35
CHRNA7 P36544 1/20 0.35
CHRNA4 P43681 1/20 0.35
NISCH Q9Y2I1 4/20 0.35
MAOA P21397 2/20 0.35
MAOB P27338 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6299004 0.72 TP53 (0.39) IGF1RALOX15TP53L3MBTL1
SCHEMBL1828656 0.69 TP53 (0.42) IGF1RALOX15TP53L3MBTL1
SCHEMBL9090818 0.68 IGF1R (0.42) IGF1RALOX15TP53L3MBTL1CHRNB2
SCHEMBL28646643 0.66 GAA (0.45)
SCHEMBL15541676 0.65 TSHR (0.47)
SCHEMBL8342164 0.65 NISCH (0.33) NISCH
SCHEMBL16179411 0.64 TP53 (0.62) IGF1RALOX15TP53L3MBTL1
SCHEMBL6762506 0.64 TP53 (0.62) IGF1RALOX15TP53L3MBTL1
SCHEMBL5254610 0.64 TP53 (0.41) IGF1RALOX15TP53L3MBTL1
SCHEMBL23532575 0.63 IGF1R (0.35) IGF1RALOX15TP53L3MBTL1CHRNB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6852193-B2 Semi-solid one- or two-part compositions LOCTITE (R&D) LIMITED (IE) 2005-02-08 US claimed
US-20030171467-A1 Semi-solid one- or two-part compositions LOCTITE (R&D) LIMITED (IE) 2003-09-11 US claimed
WO-2001092434-A1 SEMI-SOLID ONE- OR TWO-PART COMPOSITIONS LOCTITE (R & D) LIMITED (IE) 2001-12-06 WO claimed
EP-0502733-B1 Air-activatable polymerisable compositions LOCTITE IRELAND LTD (IE) 1997-09-10 EP claimed
EP-0502733-A1 Air-activatable polymerisable compositions LOCTITE (IRELAND) Ltd. (IE) 1992-09-09 EP claimed
US-6852193-B2 Semi-solid one- or two-part compositions LOCTITE (R&D) LIMITED (IE) 2005-02-08 US disclosed
US-20030171467-A1 Semi-solid one- or two-part compositions LOCTITE (R&D) LIMITED (IE) 2003-09-11 US disclosed
WO-2001092434-A1 SEMI-SOLID ONE- OR TWO-PART COMPOSITIONS LOCTITE (R & D) LIMITED (IE) 2001-12-06 WO disclosed
US-5683536-A PEROXIDE-FREE AUTOOXIDIZABLE FREE RADICAL CATALYST LOCTITE LTD. (IE) 1997-11-04 US disclosed
US-5523347-A CONTAINS PARTIALLY HYDROGENATED PYRIDINES, CONDENSATION PRODUCT OF CYCLIC KETONES AND UREAS, SCHIFF'S BASE, INDOLES, PYRROLES, IMIDAZOLES, PIPERAZINES, CARBAZOLES AND TETRAHYDROQUNOLINES AS ACTIVATOR LOCTITE (IRELAND) LIMITED (IE) 1996-06-04 US disclosed
EP-0502733-A1 Air-activatable polymerisable compositions LOCTITE (IRELAND) Ltd. (IE) 1992-09-09 EP disclosed