Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGT1A1 | P22309 | 3/20 | 0.59 |
| ▸ | MLNR | O43193 | 1/20 | 0.59 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.59 |
| ▸ | SLCO2B1 | O94956 | 1/20 | 0.59 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.59 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.59 |
| ▸ | CCKAR | P32238 | 1/20 | 0.59 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.59 |
| ▸ | GHSR | Q92847 | 1/20 | 0.59 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.59 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.59 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | CTSD | P07339 | 3/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 11/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 11/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 11/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 11/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 11/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6157294 | 0.91 | MLNR (0.47) | UGT1A1MLNRNR1I2SLCO2B1ABCB11 | |
| SCHEMBL6105 | 0.91 | MLNR (0.47) | UGT1A1MLNRNR1I2SLCO2B1ABCB11 | |
| SCHEMBL7547851 | 0.89 | UGT1A1 (0.65) | UGT1A1MLNRNR1I2SLCO2B1ABCB11 | |
| SCHEMBL5977 | 0.88 | UGT1A1 (0.66) | UGT1A1MLNRNR1I2SLCO2B1ABCB11 | |
| SCHEMBL6169 | 0.87 | UGT1A1 (0.67) | UGT1A1MLNRNR1I2SLCO2B1ABCB11 | |
| SCHEMBL5960 | 0.86 | MLNR (0.43) | UGT1A1MLNRNR1I2SLCO2B1ABCB11 | |
| SCHEMBL6156660 | 0.86 | MLNR (0.43) | UGT1A1MLNRNR1I2SLCO2B1ABCB11 | |
| SCHEMBL6749 | 0.86 | UGT1A1 (0.67) | UGT1A1MLNRNR1I2SLCO2B1ABCB11 | |
| SCHEMBL6867 | 0.85 | UGT1A1 (0.64) | UGT1A1MLNRNR1I2SLCO2B1ABCB11 | |
| SCHEMBL6596 | 0.84 | UGT1A1 (0.63) | UGT1A1MLNRNR1I2SLCO2B1ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0900210-B1 | ANTIVIRALLY ACTIVE HETEROCYCLIC AZAHEXANE DERIVATIVES | NOVARTIS AG (CH) | 2005-02-09 | — | — | EP | disclosed |
| EP-0943668-B1 | Process of improving the leveling of a floor polish composition | ROHM & HAAS (US) | 2005-02-09 | — | — | EP | disclosed |
| EP-0900833-B1 | Polymer for improving the burnish response of a floor polish | ROHM & HAAS (US) | 2004-06-30 | — | — | EP | disclosed |
| US-6548596-B1 | Aqueous suspension of water insoluble butyl methacrylate-isobutyl methacrylate copolymer comprising acid monomer; floor polish burnish response | ROHM AND HAAS COMPANY | 2003-04-15 | — | — | US | disclosed |
| US-6300519-B1 | REACTING HYDRAZINE DERIVATIVE WITH EPOXIDE COMPOUND | NOVARTIS FINANCE CORPORATION | 2001-10-09 | — | — | US | disclosed |
| US-6166004-A | Combinations of HIV protease inhibitors with reverse transcriptase inhibitors | NOVARTIS FINANCE CORPORATION (US) | 2000-12-26 | — | — | US | disclosed |
| US-6110946-A | AN ENZYME INHIBITORS OF RETROVIRAL ASPARTATE PROTEASE FOR THE TREATMENT OF AIDS | NOVARTIS FINANCE CORPORATION (US) | 2000-08-29 | — | — | US | disclosed |
| US-6043314-A | DIVALENT COPPER ION CROSSLINKING AGENT, POLYMER BEING PREPARED FROM MORE THAN ONE ETHYLENICALLY UNSATURATED MONOMER AND ACID CONTAININGFUNCTIONAL RESIDUES, | ROHM AND HAAS COMPANY (US) | 2000-03-28 | — | — | US | disclosed |
| EP-0943668-A1 | Process of improving the leveling of a floor polish composition | ROHM AND HAAS COMPANY (US) | 1999-09-22 | — | — | EP | disclosed |
| EP-0943669-A1 | Process of improving the appearance of a floor polish composition | ROHM AND HAAS COMPANY (US) | 1999-09-22 | — | — | EP | disclosed |
| EP-0900833-A1 | Polymer for improving the burnish response of a floor polish | ROHM AND HAAS COMPANY (US) | 1999-03-10 | — | — | EP | disclosed |
| EP-0900210-A1 | ANTIVIRALLY ACTIVE HETEROCYCLIC AZAHEXANE DERIVATIVES | Novartis AG (CH) | 1999-03-10 | — | — | EP | disclosed |
| US-5849911-A | Antivirally active heterocyclic azahexane derivatives | NOVARTIS FINANCE CORPORATION (US) | 1998-12-15 | — | — | US | disclosed |
| WO-1997040029-A1 | ANTIVIRALLY ACTIVE HETEROCYCLIC AZAHEXANE DERIVATIVES | NOVARTIS AG (CH) | 1997-10-30 | — | — | WO | disclosed |
| EP-0120712-B1 | POLISH COMPOSITIONS AND POLISH VEHICLES USEFUL THEREIN | ROHM AND HAAS COMPANY (US) | 1987-06-24 | — | — | EP | disclosed |
| EP-0120712-A2 | Polish compositions and polish vehicles useful therein | ROHM AND HAAS COMPANY (US) | 1984-10-03 | — | — | EP | disclosed |