Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 6/20 | 0.44 |
| ▸ | CA1 | P00915 | 5/20 | 0.44 |
| ▸ | CES2 | O00748 | 5/20 | 0.43 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL23327569 | 1.00 | CES1 (0.44) | CES1CA1CES2FFAR3HDAC3 | |
| Acetic Acid SCHEMBL11663016 | 1.00 | CES1 (0.44) | CES1CA1CES2FFAR3HDAC3 | |
| Acetic Acid SCHEMBL10615948 | 0.95 | CES1 (0.41) | CES1CA1CES2FFAR3HDAC3 | |
| Acetic Acid SCHEMBL11052089 | 0.92 | CES1 (0.46) | CES1CA1CES2ALDH1A1CA2 | |
| Bicarbonate SCHEMBL8729890 | 0.92 | CA1 (0.46) | CES1CA1CES2FFAR3HDAC3 | |
| Acetic Acid SCHEMBL674336 | 0.90 | CES1 (0.48) | CES1CA1CES2ALDH1A1CA2 | |
| Acetic Acid SCHEMBL15529625 | 0.90 | CES1 (0.48) | CES1CA1CES2ALDH1A1CA2 | |
| Acetic Acid SCHEMBL11301673 | 0.90 | CES1 (0.41) | CES1CA1CES2FFAR3HDAC3 | |
| Acetic Acid SCHEMBL2695510 | 0.90 | CES1 (0.48) | CES1CA1CES2ALDH1A1CA2 | |
| Acetic Acid SCHEMBL15529776 | 0.90 | CES1 (0.48) | CES1CA1CES2ALDH1A1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3293 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260015521-A1 | THERMOSETTING COATING COMPOSITION WITH IMPROVED SCRATCH RESISTANCE | EASTMAN CHEMICAL COMPANY (US) | 2026-01-15 | — | — | US | claimed |
| US-12421417-B2 | Thermosetting coating composition with improved scratch resistance | EASTMAN CHEMICAL COMPANY (US) | 2025-09-23 | — | — | US | claimed |
| CN-119684755-A | 1,4:3, 6-Diglycidyl hexaol polyester/nano rubber particle blend material, preparation method and application thereof | 中国科学院化学研究所 | 2025-03-25 | — | — | CN | claimed |
| CN-118553899-B | Asphalt-based hard carbon composite material, preparation method thereof and sodium ion battery | 国科炭美新材料(湖州)有限公司 | 2025-02-07 | — | — | CN | claimed |
| CN-118553899-A | Asphalt-based hard carbon composite material, preparation method thereof and sodium ion battery | 国科炭美新材料(湖州)有限公司 | 2024-08-27 | — | — | CN | claimed |
| CN-117757376-A | Direct-collecting easy-unreeling polyurethane pressure-sensitive adhesive protective film and preparation method thereof | 湖北航天化学新材料科技有限公司 | 2024-03-26 | — | — | CN | claimed |
| CN-117683214-A | Synthesis method of poly 3-hydroxy fatty acid ester | 联泓(江苏)新材料研究院有限公司 | 2024-03-12 | — | — | CN | claimed |
| CN-113461529-B | Preparation method of 2-methyl-4-chlorophenoxyacetic acid isooctyl ester | 利尔化学股份有限公司 | 2023-10-31 | — | — | CN | claimed |
| CN-113881210-B | High-flow transparent polycarbonate material and preparation method thereof | 万华化学集团股份有限公司 | 2023-08-11 | — | — | CN | claimed |
| CN-115667361-A | Autocatalytic rapid degradation polyester polymer and preparation method and application thereof | 埃德温·W·黄 | 2023-01-31 | — | — | CN | claimed |
| US-4288496-A | Silicone polymer-based release coating agents having organic titanates as stabilizers and tapes | PHILLIPS PETROLEUM COMPANY (US) | 1981-09-08 | — | — | US | claimed |
| US-4270953-A | STORAGE STABILITY | KANSAI PAINT CO., LTD. (JP) | 1981-06-02 | — | — | US | claimed |
| EP-0028345-A1 | Method of preparing thermoplastic aromatic polyphosphonates with thermal ageing resistance, and their use | BAYER AG (DE) | 1981-05-13 | — | — | EP | claimed |
| US-4261876-A | VARIATIONS IN RELEASE FORCE STRENGTH; ADHESIVE TAPES | PHILLIPS PETROLEUM COMPANY (US) | 1981-04-14 | — | — | US | claimed |
| US-4241101-A | ELECTROSTATIC POWDER COATING | WESTINGHOUSE ELECTRIC CORP. (US) | 1980-12-23 | — | — | US | claimed |
| EP-0000879-B1 | PROCESS FOR THE PREPARATION OF AROMATIC CARBONIC ACID ESTERS | BAYER AG (DE) | 1980-08-20 | — | — | EP | claimed |
| US-4216187-A | Method of detoxifying organotin-containing paint residues | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF TRANSPORTATION (US) | 1980-08-05 | — | — | US | claimed |
| EP-0000879-A1 | Process for the preparation of aromatic carbonic acid esters | BAYER AG (DE) | 1979-03-07 | — | — | EP | claimed |
| US-4101692-A | TOP COATING WITH EPOXY RESIN, CURING AGENT, AND CEMENT | SOUTHERN IMPERIAL COATINGS CORPORATION (US) | 1978-07-18 | — | — | US | claimed |
| US-4066588-A | MODIFIED ALKYD RESIN, POLYISOCYANATE, CURING ACCELERATOR | SUMITOMO DUREZ COMPANY, LTD. (JA) | 1978-01-03 | — | — | US | claimed |