Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 4/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | SCN1A | P35498 | 1/20 | 0.49 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.49 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.49 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6298658 | 1.00 | STS (0.60) | STSSMN1; SMN2LMNAMAPTNPSR1 | |
| SCHEMBL4242989 | 1.00 | STS (0.60) | STSSMN1; SMN2LMNAMAPTNPSR1 | |
| SCHEMBL29283750 | 0.98 | STS (0.59) | STSSMN1; SMN2LMNAMAPTNPSR1 | |
| SCHEMBL14545540 | 0.95 | STS (0.56) | STSSMN1; SMN2LMNAMAPTNPSR1 | |
| SCHEMBL110657 | 0.92 | SMN1; SMN2 (0.68) | STSSMN1; SMN2LMNAMAPTNPSR1 | |
| SCHEMBL27647587 | 0.90 | SMN1; SMN2 (0.66) | STSSMN1; SMN2LMNAMAPTNPSR1 | |
| SCHEMBL27668237 | 0.90 | SMN1; SMN2 (0.66) | STSSMN1; SMN2LMNAMAPTNPSR1 | |
| SCHEMBL27647562 | 0.90 | SMN1; SMN2 (0.66) | STSSMN1; SMN2LMNAMAPTNPSR1 | |
| SCHEMBL27647429 | 0.90 | SMN1; SMN2 (0.66) | STSSMN1; SMN2LMNAMAPTNPSR1 | |
| SCHEMBL27647433 | 0.90 | SMN1; SMN2 (0.66) | STSSMN1; SMN2LMNAMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180116993-A1 | MODULATORS OF FARNESOID X RECEPTOR AND METHODS FOR THE USE THEREOF | XIAMEN UNIVERSITY (CN) | 2018-05-03 | — | — | US | claimed |
| WO-2016116054-A1 | MODULATORS OF FARNESOID X RECEPTOR AND METHODS FOR THE USE THEREOF | XIAMEN UNIVERSITY (CN) | 2016-07-28 | — | — | WO | claimed |
| US-20180116993-A1 | MODULATORS OF FARNESOID X RECEPTOR AND METHODS FOR THE USE THEREOF | XIAMEN UNIVERSITY (CN) | 2018-05-03 | — | — | US | disclosed |
| US-20180116993-A1 | MODULATORS OF FARNESOID X RECEPTOR AND METHODS FOR THE USE THEREOF | XIAMEN UNIVERSITY (CN) | 2018-05-03 | — | — | US | disclosed |
| US-20180116993-A1 | MODULATORS OF FARNESOID X RECEPTOR AND METHODS FOR THE USE THEREOF | XIAMEN UNIVERSITY (CN) | 2018-05-03 | — | — | US | disclosed |
| WO-2016116054-A1 | MODULATORS OF FARNESOID X RECEPTOR AND METHODS FOR THE USE THEREOF | XIAMEN UNIVERSITY (CN) | 2016-07-28 | — | — | WO | disclosed |
| EP-1556434-B1 | POLYCARBONATES, POLYESTER CARBONATES AND POLYESTERS CONTAINING CYCLOALKYL-SUBSTITUTED PHENOLS IN A LATERAL POSITION | BAYER MATERIALSCIENCE AG (DE) | 2007-10-17 | — | — | EP | disclosed |
| US-6916899-B2 | Polycarbonates, polyester carbonates and polyesters having lateral, cycloalkyl-substituted phenols | BAYER AKTIENGESELLSCHAFT (DE) | 2005-07-12 | — | — | US | disclosed |
| US-20040158025-A1 | Polycarbonates, polyester carbonates and polyesters having lateral, cycloalkyl-substituted phenols | BAYER AKTIENGESELLSCHAFT (DE) | 2004-08-12 | — | — | US | disclosed |
| US-20040127677-A1 | Polycarbonates, polyester carbonates and polyesters having lateral, cycloalkyl-substituted phenols | BAYER AKTIENGESELLSCHAFT (DE) | 2004-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180116993-A1 | MODULATORS OF FARNESOID X RECEPTOR AND METHODS FOR THE USE THEREOF | NR1H4, FABP1, NR1H2 | STS 3261/4885SMN1; SMN2 4843/4885LMNA 3367/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.