Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6762331 | 0.94 | TACR1 (0.89) | TACR1 | |
| SCHEMBL6767451 | 0.91 | TACR1 (0.84) | TACR1 | |
| Lanepitant SCHEMBL30522773 | 0.91 | TACR1 (1.00) | TACR1 | |
| Lanepitant SCHEMBL30695554 | 0.91 | TACR1 (1.00) | TACR1 | |
| Lanepitant SCHEMBL14421491 | 0.91 | TACR1 (1.00) | TACR1 | |
| Lanepitant SCHEMBL121512 | 0.91 | TACR1 (1.00) | TACR1 | |
| Lanepitant SCHEMBL6904907 | 0.91 | TACR1 (1.00) | TACR1 | |
| Lanepitant SCHEMBL7823239 | 0.90 | TACR1 (0.99) | TACR1 | |
| Lanepitant SCHEMBL9079078 | 0.90 | TACR1 (0.99) | TACR1 | |
| Lanepitant SCHEMBL7833331 | 0.89 | TACR1 (0.97) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6869957-B1 | Non-peptide tachykinin receptor antagonists | ELI LILLY AND COMPANY (US) | 2005-03-22 | — | — | US | claimed |
| EP-0729468-B1 | NON-PEPTIDE TACHYKININ RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 2003-01-15 | — | — | EP | claimed |
| JP-2001509484-A | — | — | 2001-07-24 | — | — | JP | claimed |
| EP-0994712-A1 | INHIBITORS OF NEUTROPHIL MEDIATED OXIDANT PRODUCTION | ELI LILLY AND COMPANY (US) | 2000-04-26 | — | — | EP | claimed |
| WO-1999002163-A1 | INHIBITORS OF NEUTROPHIL MEDIATED OXIDANT PRODUCTION | ELI LILLY AND COMPANY (US) | 1999-01-21 | — | — | WO | claimed |
| EP-0761219-A1 | 2-Acylaminopropanamines as growth hormone secretagogues | ELI LILLY AND COMPANY (US) | 1997-03-12 | — | — | EP | claimed |
| WO-1997007117-A1 | 2-ACYLAMINOPROPANAMINES AS GROWTH HORMONE SECRETAGOGUES | ELI LILLY AND COMPANY (US) | 1997-02-27 | — | — | WO | claimed |
| WO-1995014017-A1 | NON-PEPTIDE TACHYKININ RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1995-05-26 | — | — | WO | claimed |