SCHEMBL629978

SCHEMBL629978

CCCCS(=O)(=O)C(NCCC1CCCCC1)c1ccc(C(=O)NC(CCSC)C(=O)O)c(-c2ccccc2C)c1

nearest known ligand 0.63

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FNTA P49354 1/20 0.63
FNTB P49356 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7869093 0.88 FNTA (0.67) FNTAFNTB
SCHEMBL6628776 0.87 FNTA (0.54) FNTAFNTB
SCHEMBL6628368 0.86 FNTA (0.56) FNTAFNTB
SCHEMBL8592700 0.81 FNTA (0.64) FNTAFNTB
SCHEMBL628946 0.81 FNTA (0.58) FNTAFNTB
SCHEMBL629979 0.80 FNTA (0.79) FNTAFNTB
SCHEMBL628912 0.80 FNTA (0.61) FNTAFNTB
SCHEMBL7921813 0.80 FNTA (0.63) FNTAFNTB
SCHEMBL8587495 0.80 FNTA (0.63) FNTAFNTB
SCHEMBL8589529 0.80 FNTA (0.63) FNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0986384-A4 INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES UNIV PITTSBURGH (US) 2004-09-15 EP claimed
EP-0986384-A1 INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES UNIVERSITY OF PITTSBURGH (US) 2000-03-22 EP claimed
EP-0986384-B1 INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES UNIV PITTSBURGH (US) 2012-02-22 EP disclosed