Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 14/20 | 0.70 |
| ▸ | SYK | P43405 | 14/20 | 0.70 |
| ▸ | MAPK14 | Q16539 | 12/20 | 0.70 |
| ▸ | GSK3A | P49840 | 12/20 | 0.66 |
| ▸ | LCK | P06239 | 2/20 | 0.64 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.61 |
| ▸ | TNF | P01375 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6547053 | 0.90 | SRC (0.71) | SRCSYKMAPK14GSK3ALCK | |
| SCHEMBL6545985 | 0.88 | GSK3A (0.68) | SRCSYKMAPK14GSK3ALCK | |
| SCHEMBL6298580 | 0.87 | GSK3A (0.69) | SRCSYKMAPK14GSK3ACXCL8 | |
| SCHEMBL17659974 | 0.86 | GSK3A (0.74) | SRCSYKMAPK14GSK3ALCK | |
| SCHEMBL6546000 | 0.86 | GSK3A (0.74) | SRCSYKMAPK14GSK3ALCK | |
| SCHEMBL6546013 | 0.85 | GSK3A (0.69) | SRCSYKMAPK14GSK3ALCK | |
| SCHEMBL18461774 | 0.85 | GSK3A (0.73) | SRCSYKMAPK14GSK3ALCK | |
| SCHEMBL16143036 | 0.85 | GSK3A (0.75) | SRCSYKMAPK14GSK3ALCK | |
| SCHEMBL17665876 | 0.85 | GSK3A (0.73) | SRCSYKMAPK14GSK3ALCK | |
| SCHEMBL16106281 | 0.85 | GSK3A (0.73) | SRCSYKMAPK14GSK3ALCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6852717-B2 | Compounds useful as anti-inflammatory agents | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2005-02-08 | — | — | US | disclosed |