Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.58 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.40 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6301136 | 0.97 | PPARG (0.62) | PPARGBCL2L1MCL1ALDH1A1PTGER4 | |
| SCHEMBL6308572 | 0.95 | PPARG (0.63) | PPARGBCL2L1MCL1ALDH1A1PTGER4 | |
| SCHEMBL6303474 | 0.95 | PPARG (0.62) | PPARGBCL2L1MCL1ALDH1A1PTGER4 | |
| SCHEMBL6307796 | 0.94 | PPARG (0.54) | PPARGBCL2L1MCL1ALDH1A1PTGER4 | |
| SCHEMBL7652842 | 0.94 | PPARG (0.57) | PPARGBCL2L1MCL1ALDH1A1PTGER4 | |
| SCHEMBL6134953 | 0.92 | PPARG (0.52) | PPARGBCL2L1MCL1ALDH1A1PTGER4 | |
| SCHEMBL6303634 | 0.90 | PPARG (0.57) | PPARGALDH1A1PTGER4HDAC3HDAC4 | |
| SCHEMBL7654833 | 0.88 | PPARG (0.52) | PPARGBCL2L1MCL1HDAC3HDAC4 | |
| SCHEMBL6301270 | 0.87 | PPARG (0.51) | PPARGBCL2L1MCL1ALDH1A1PTGER4 | |
| SCHEMBL6134973 | 0.87 | PPARG (0.70) | PPARGALDH1A1HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6869950-B1 | Benzimidazole derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-03-22 | — | — | US | claimed |
| EP-1142880-A1 | BENZIMIDAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-10-10 | — | — | EP | claimed |
| US-6869950-B1 | Benzimidazole derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-03-22 | — | — | US | disclosed |
| EP-1142880-A1 | BENZIMIDAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-10-10 | — | — | EP | disclosed |