Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 10/20 | 0.55 |
| ▸ | RORC | P51449 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.45 |
| ▸ | CCR2 | P41597 | 1/20 | 0.42 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6301625 | 0.90 | PPARG (0.63) | PPARGRORCHDAC1HDAC6HDAC3 | |
| SCHEMBL6303697 | 0.90 | PPARG (0.60) | PPARGRORCHDAC1HDAC6HDAC3 | |
| SCHEMBL6304245 | 0.90 | PPARG (0.64) | PPARGRORCHDAC1HDAC6HDAC3 | |
| SCHEMBL7654248 | 0.89 | PPARG (0.52) | PPARGRORCHDAC1HDAC6HDAC3 | |
| SCHEMBL1160331 | 0.89 | PPARG (0.57) | PPARGRORCHDAC1HDAC6HDAC3 | |
| SCHEMBL6307858 | 0.89 | PPARG (0.64) | PPARGRORCHDAC1HDAC6HDAC3 | |
| SCHEMBL6135129 | 0.89 | PPARG (0.56) | PPARGRORCHDAC1HDAC6HDAC3 | |
| SCHEMBL7654833 | 0.88 | PPARG (0.52) | PPARGRORCHDAC1HDAC6HDAC3 | |
| SCHEMBL6134973 | 0.87 | PPARG (0.70) | PPARGHDAC1HDAC6HDAC3HDAC4 | |
| SCHEMBL6303913 | 0.87 | PPARG (0.55) | PPARGRORCHDAC1HDAC6HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1142880-A1 | BENZIMIDAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-10-10 | — | — | EP | claimed |
| US-6869950-B1 | Benzimidazole derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-03-22 | — | — | US | disclosed |
| EP-1142880-A1 | BENZIMIDAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-10-10 | — | — | EP | disclosed |