Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.58 |
| ▸ | AGTR1 | P30556 | 8/20 | 0.50 |
| ▸ | AGTR2 | P50052 | 8/20 | 0.50 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.44 |
| ▸ | RARB | P10826 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RARA | P10276 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6301633 | 1.00 | PPARG (0.58) | PPARGAGTR1AGTR2PLA2G4ARARB | |
| SCHEMBL6301628 | 0.99 | PPARG (0.59) | PPARGAGTR1AGTR2PLA2G4ARARB | |
| SCHEMBL6303561 | 0.96 | PPARG (0.57) | PPARGAGTR1AGTR2 | |
| SCHEMBL6309536 | 0.90 | PPARG (0.56) | PPARGAGTR1AGTR2MEN1ALDH1A1 | |
| SCHEMBL6308739 | 0.90 | PPARG (0.56) | PPARGAGTR1AGTR2MEN1ALDH1A1 | |
| SCHEMBL6307861 | 0.89 | PPARG (0.56) | PPARGAGTR1AGTR2MEN1ALDH1A1 | |
| SCHEMBL6309647 | 0.88 | PPARG (0.54) | PPARGAGTR1AGTR2 | |
| SCHEMBL27465431 | 0.86 | PPARG (0.52) | PPARGAGTR1AGTR2 | |
| SCHEMBL6303646 | 0.86 | PPARG (0.57) | PPARGAGTR1AGTR2PLA2G4ARARB | |
| SCHEMBL6308005 | 0.86 | PPARG (0.57) | PPARGAGTR1AGTR2PLA2G4ARARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6869950-B1 | Benzimidazole derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-03-22 | — | — | US | disclosed |
| EP-1142880-A1 | BENZIMIDAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-10-10 | — | — | EP | disclosed |