Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.71 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 8/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
| ▸ | KIT | P10721 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6134256 | 0.98 | PPARG (0.75) | PPARGHDAC1HDAC6HDAC3HDAC4 | |
| SCHEMBL6304186 | 0.88 | PPARG (0.76) | PPARGHDAC1HDAC6HDAC3HDAC4 | |
| SCHEMBL6308746 | 0.88 | PPARG (0.56) | PPARGHDAC1HDAC6HDAC3HDAC4 | |
| SCHEMBL6308742 | 0.88 | PPARG (0.56) | PPARGHDAC1HDAC6HDAC3HDAC4 | |
| SCHEMBL6134720 | 0.86 | PPARG (0.80) | PPARGHDAC1HDAC6HDAC3HDAC4 | |
| SCHEMBL1160177 | 0.85 | PPARG (0.95) | PPARGHDAC1HDAC6HDAC3HDAC4 | |
| SCHEMBL7648938 | 0.85 | PPARG (0.53) | PPARGHDAC1HDAC6HDAC3HDAC4 | |
| SCHEMBL7650777 | 0.85 | PPARG (0.91) | PPARGHDAC1HDAC6HDAC3HDAC4 | |
| SCHEMBL6134751 | 0.85 | PPARG (0.71) | PPARGHDAC1HDAC6HDAC3HDAC4 | |
| SCHEMBL1160232 | 0.85 | PPARG (0.78) | PPARGHDAC1HDAC6HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6869950-B1 | Benzimidazole derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-03-22 | — | — | US | disclosed |
| EP-1142880-A1 | BENZIMIDAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-10-10 | — | — | EP | disclosed |