Methane

Methane

SCHEMBL6301524

C.CCC(=O)Oc1ccccc1

nearest known ligand 0.70

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.70
KMT2A Q03164 5/20 0.60
ESR1 P03372 2/20 0.60
HIF1A Q16665 2/20 0.60
SMN1; SMN2 Q16637 2/20 0.60
RECQL P46063 1/20 0.60
ACHE P22303 2/20 0.56
HTT P42858 3/20 0.51
RAB9A P51151 2/20 0.51
LMNA P02545 2/20 0.51
MAPT P10636 5/20 0.50
NPC1 O15118 1/20 0.50
NFKB1 P19838 1/20 0.50
NFKB2 Q00653 1/20 0.50
RELA Q04206 1/20 0.50
CYP19A1 P11511 1/20 0.50
TP53 P04637 1/20 0.49
MEN1 O00255 1/20 0.49
ALDH1A1 P00352 1/20 0.45
HSD17B10 Q99714 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL28089483 0.98 ELANE (0.72) ELANEKMT2AESR1HIF1ASMN1; SMN2
SCHEMBL45119 0.98 ELANE (0.72) ELANEKMT2AESR1HIF1ASMN1; SMN2
SCHEMBL9799566 0.98 ELANE (0.72) ELANEKMT2AESR1HIF1ASMN1; SMN2
Magnesium SCHEMBL31307540 0.96 ELANE (0.70) ELANEKMT2AESR1HIF1ASMN1; SMN2
SCHEMBL8467278 0.96 ELANE (0.70) ELANEKMT2AESR1HIF1ASMN1; SMN2
SCHEMBL30209196 0.96 ELANE (0.70) ELANEKMT2AESR1HIF1ASMN1; SMN2
SCHEMBL376108 0.96 ELANE (0.70) ELANEKMT2AESR1HIF1ASMN1; SMN2
SCHEMBL17028724 0.96 ELANE (0.70) ELANEKMT2AESR1HIF1ASMN1; SMN2
Ammonia Solution, Strong SCHEMBL22042017 0.96 ELANE (0.70) ELANEKMT2AESR1HIF1ASMN1; SMN2
SCHEMBL31575762 0.96 ELANE (0.70) ELANEKMT2AESR1HIF1ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6902785-B2 Laminar structure DENOVUS LLC (US) 2005-06-07 US disclosed
US-20040157056-A1 Laminar structure BLUE GOO LLC 2004-08-12 US disclosed
US-6638590-B2 Tacky mastic in contact with ultraviolet light and moisture barrier; for protection of wood, metal, concrete, cement DENOVUS LLC 2003-10-28 US disclosed
US-20020090478-A1 LAMINAR STRUCTURE DENOVUS L.L.C. 2002-07-11 US disclosed
EP-0085968-B1 NUCLEATING AGENT FOR CRYSTALLINE OLEFINIC POLYMERS MONTEFINA S.A. (BE) 1986-01-02 EP disclosed