⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6301871 | 0.91 | — | — | |
| SCHEMBL6301742 | 0.89 | TRPV1 (0.58) | — | |
| SCHEMBL6302045 | 0.88 | TRPV1 (0.58) | — | |
| SCHEMBL6304294 | 0.85 | — | — | |
| SCHEMBL6301868 | 0.85 | — | — | |
| SCHEMBL6304298 | 0.81 | — | — | |
| SCHEMBL6301842 | 0.80 | TRPV1 (0.57) | — | |
| SCHEMBL6305016 | 0.78 | TRPV1 (0.55) | — | |
| SCHEMBL6375788 | 0.77 | TRPV1 (0.62) | — | |
| SCHEMBL6301775 | 0.77 | TRPV1 (0.74) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6872748-B2 | Simplified resiniferatoxin analogues as vanilloid receptor agonist showing excellent analgesic activity and the pharmaceutical compositions containing the same | DIGITAL BIOTECH CO., LTD. (KR) | 2005-03-29 | — | — | US | disclosed |
| US-20040063786-A1 | Simplified resiniferatoxin analogues as vanilloid receptor agonist showing excellent analgesic activity and the pharmaceutical compositions containing the same | MEDIFRON DBT CO., LTD. (KR) | 2004-04-01 | — | — | US | disclosed |