⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29483856 | 1.00 | — | — | |
| Fluoride SCHEMBL27460684 | 0.97 | — | — | |
| SCHEMBL2234570 | 0.92 | TDP1 (0.44) | — | |
| Methyl Alcohol SCHEMBL17255950 | 0.92 | TDP1 (0.39) | — | |
| Cyanide SCHEMBL28136065 | 0.92 | RPS6KA5 (0.35) | — | |
| Pyrazine SCHEMBL23856033 | 0.92 | RPS6KA5 (0.35) | — | |
| SCHEMBL29236946 | 0.90 | RPS6KA5 (0.38) | — | |
| SCHEMBL11481575 | 0.86 | NAPRT (0.41) | — | |
| Formamide SCHEMBL27578500 | 0.86 | LOX (0.32) | — | |
| Pyridine SCHEMBL28152590 | 0.86 | TDP1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 13411 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122010902-A | Carbonyl substituted pyrimidine HIV-1 reverse transcriptase inhibitor and preparation method and application thereof | 山东大学 | 2026-05-12 | — | — | CN | claimed |
| US-20260103457-A1 | NOVEL PROCESS FOR PREPARATION OF SOLUBLE GUANYLATE CYCLASE STIMULATORS | CYCLERION THERAPEUTICS INC (US) | 2026-04-16 | — | — | US | claimed |
| EP-4692075-A1 | USE OF A MECHANICAL FORCE IN THE PROCESS OF PREPARATION OF OSIMERTINIB | Université de Montpellier (FR) | 2026-02-11 | — | — | EP | claimed |
| WO-2025129105-A1 | COMPOSITION AND METHOD FOR DETECTION OF BIOMOLECULES VIA AROMATIC LABELING USING HETEROCYCLIC COMPOUNDS | Life Technologies Corporation (US) | 2025-06-19 | — | — | WO | claimed |
| CN-120091759-A | Fungicide mixtures for effective insecticidal control | 安道麦马克西姆有限公司 | 2025-06-03 | — | — | CN | claimed |
| WO-2025102245-A1 | SYNTHESIS METHOD FOR DUAL ENDOTHELIN RECEPTOR ANTAGONIST APROCITENTAN | 浙江天宇药业股份有限公司 | 2025-05-22 | — | — | WO | claimed |
| CN-119775259-B | Amatinib intermediate Synthesis method of intermediate | 烟台舜康生物科技有限公司 | 2025-05-13 | — | — | CN | claimed |
| CN-119817584-A | Synergistic binary composition containing two active components and application thereof | 沈阳中化农药化工研发有限公司 | 2025-04-15 | — | — | CN | claimed |
| CN-119775259-A | Amatinib intermediate Synthesis method of intermediate | 烟台舜康生物科技有限公司 | 2025-04-08 | — | — | CN | claimed |
| CN-118772112-B | PROTAC medicine molecule targeting Fam20C as well as preparation method and application thereof | 西南交通大学 | 2025-04-01 | — | — | CN | claimed |
| EP-0176304-A1 | Herbicidal pyrazolesulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-04-02 | — | — | EP | claimed |
| EP-0159287-A1 | Use of quinoline derivatives to protect cultivated plants | CIBA-GEIGY AG (CH) | 1985-10-23 | — | — | EP | claimed |
| EP-0159290-A1 | Use of quinoline derivatives to protect cultivated plants | CIBA-GEIGY AG (CH) | 1985-10-23 | — | — | EP | claimed |
| EP-0063509-B1 | 2-PIPERAZINO-PYRIMIDINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION, MEDICAMENTS CONTAINING THEM AND THEIR USE AS INTERMEDIATES IN THE MANUFACTURE OF MEDICAMENTS | PHARMUKA LABORATOIRES (FR) | 1985-02-20 | — | — | EP | claimed |
| EP-0009154-B1 | COMPLEXES OF 9-HYDROXYALKYL-PURINES, PROCESSES FOR PREPARING THEM AND THERAPEUTICAL COMPOSITIONS CONTAINING THE COMPLEXES AS ACTIVE INGREDIENTS | Newport Pharmaceuticals International, Inc. (US) | 1982-12-08 | — | — | EP | claimed |
| EP-0009155-B1 | 9-HYDROXYALKYL-PURINES, PROCESSES FOR PREPARING THEM AND THERAPEUTICAL COMPOSITION CONTAINING THE 9-HYDROXYALKYL-PURINES AS ACTIVE INGREDIENTS | Newport Pharmaceuticals International, Inc. (US) | 1982-11-17 | — | — | EP | claimed |
| EP-0063509-A1 | 2-Piperazino-pyrimidine derivatives, processes for their preparation, medicaments containing them and their use as intermediates in the manufacture of medicaments | PHARMUKA LABORATOIRES (FR) | 1982-10-27 | — | — | EP | claimed |
| EP-0046677-A2 | Herbicidal sulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-03-03 | — | — | EP | claimed |
| US-4278433-A | CELLULOSE TEXTILES, BISULFITE ADDITION PRODUCT | BASF AKTIENGESELLSCHAFT (DE) | 1981-07-14 | — | — | US | claimed |
| US-4119460-A | FUSED CARBOCYCLIC RING COMPOUNDS, POLYPHENYL COMPOUNDS NITROGEN-FREE POLYARYLATED COMPOUNDS | EASTMAN KODAK COMPANY (US) | 1978-10-10 | — | — | US | claimed |