Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 6/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.57 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 6/20 | 0.43 |
| ▸ | CA12 | O43570 | 5/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 4/20 | 0.42 |
| ▸ | CA7 | P43166 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA3 | P07451 | 2/20 | 0.42 |
| ▸ | CA4 | P22748 | 2/20 | 0.42 |
| ▸ | CA6 | P23280 | 2/20 | 0.42 |
| ▸ | CA5A | P35218 | 2/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.42 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29538674 | 1.00 | CYP2A6 (0.57) | CYP2A6ALOX12GSTP1TDP1ALDH1A1 | |
| SCHEMBL7905240 | 0.87 | GSTP1 (0.48) | CYP2A6ALOX12GSTP1TDP1ALDH1A1 | |
| SCHEMBL2637812 | 0.76 | CYP2A6 (0.80) | CYP2A6ALOX12TDP1ALDH1A1HSD17B10 | |
| Naphthalene SCHEMBL1484085 | 0.76 | CYP2A6 (0.44) | CYP2A6ALOX12GSTP1TDP1ALDH1A1 | |
| Naphthalene SCHEMBL1332240 | 0.76 | CYP2A6 (1.00) | CYP2A6ALOX12TDP1ALDH1A1HSD17B10 | |
| Naphthalene SCHEMBL1331142 | 0.76 | CYP2A6 (1.00) | CYP2A6ALOX12TDP1ALDH1A1HSD17B10 | |
| Naphthalene SCHEMBL1330659 | 0.76 | CYP2A6 (1.00) | CYP2A6ALOX12TDP1ALDH1A1HSD17B10 | |
| Naphthalene SCHEMBL8613802 | 0.76 | CYP2A6 (1.00) | CYP2A6ALOX12TDP1ALDH1A1HSD17B10 | |
| Naphthalene SCHEMBL8953 | 0.76 | CYP2A6 (1.00) | CYP2A6ALOX12TDP1ALDH1A1HSD17B10 | |
| Naphthalene SCHEMBL29358073 | 0.76 | CYP2A6 (1.00) | CYP2A6ALOX12TDP1ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4341261-A1 | AXL COMPOUNDS | Arcus Biosciences, Inc. (US) | 2024-03-27 | — | — | EP | disclosed |
| WO-2022246177-A1 | AXL COMPOUNDS | ARCUS BIOSCIENCES, INC. (US) | 2022-11-24 | — | — | WO | disclosed |
| US-6846833-B2 | Vitronectin receptor antagonist bicyclic compounds, preparation method and compositions containing same | LES LABORATORIES SERVIER (FR) | 2005-01-25 | — | — | US | disclosed |
| EP-1268429-B1 | VITRONECTIN RECEPTOR ANTAGONIST BICYCLIC COMPOUNDS, PREPARATION METHOD AND COMPOSITIONS CONTAINING SAME | SERVIER LAB (FR) | 2004-08-18 | — | — | EP | disclosed |
| EP-1268429-A1 | VITRONECTIN RECEPTOR ANTAGONIST BICYCLIC COMPOUNDS, PREPARATION METHOD AND COMPOSITIONS CONTAINING SAME | Les Laboratoires Servier (FR) | 2003-01-02 | — | — | EP | disclosed |
| WO-2001079172-A1 | VITRONECTIN RECEPTOR ANTAGONIST BICYCLIC COMPOUNDS, PREPARATION METHOD AND COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER Departament Brevets/Fontanes (FR) | 2001-10-25 | — | — | WO | disclosed |
| EP-0872903-B1 | Method for making hydrogen storage alloy powder and electrode comprising the alloy powder | SHINETSU CHEMICAL CO (JP) | 2001-10-04 | — | — | EP | disclosed |
| US-6277519-B1 | QUENCHING AN ALLOY MELT; COMMINUTION | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2001-08-21 | — | — | US | disclosed |
| US-6096144-A | TREATING WITH ACIDIC OR ALKALINE SOLUTION OF CONJUGATED UNSATURATED COMPOUND WITH AT LEAST 5 BONDS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2000-08-01 | — | — | US | disclosed |
| US-5858571-A | TREATING A PULVERIZED HYDROGEN ABSORBING ALLOY WITH A SOLUTION COMPRISING A CONJUGATED UNSATURATED COMPOUND | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1999-01-12 | — | — | US | disclosed |
| WO-1998051687-A1 | PIPERIDINO DERIVATIVES WHICH PROMOTE GROWTH HORMONE RELEASE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-11-19 | — | — | WO | disclosed |
| EP-0872903-A1 | Method for making hydrogen storage alloy powder and electrode comprising the alloy powder | Shin-Etsu Chemical Co., Ltd. (JP) | 1998-10-21 | — | — | EP | disclosed |
| EP-0332064-A2 | Benzocycloheptene derivatives, pharmaceutical preparations containing these compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1989-09-13 | — | — | EP | disclosed |
| US-4758639-A | Process for production of vinyl polymer | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1988-07-19 | — | — | US | disclosed |
| EP-0172427-A2 | Process for production of vinyl chloride polymer | Shin-Etsu Chemical Co., Ltd. (JP) | 1986-02-26 | — | — | EP | disclosed |