SCHEMBL630279

SCHEMBL630279

CCCC=CC=CCCCC

nearest known ligand 0.54

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.54
ALDH1A1 P00352 2/20 0.54
FASN P49327 1/20 0.46
FAAH O00519 5/20 0.40
TRPV1 Q8NER1 1/20 0.40
F7 P08709 1/20 0.39
F3 P13726 1/20 0.39
KDM4E B2RXH2 1/20 0.38
CNR1 P21554 2/20 0.36
CNR2 P34972 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2273586 1.00 TSHR (0.54) TSHRALDH1A1FASNFAAHTRPV1
SCHEMBL2274584 0.94 TSHR (0.59) TSHRALDH1A1FASNFAAHTRPV1
SCHEMBL2274578 0.94 TSHR (0.59) TSHRALDH1A1FASNFAAHTRPV1
SCHEMBL26905336 0.94 TSHR (0.59) TSHRALDH1A1FASNFAAHTRPV1
SCHEMBL29563802 0.91 TSHR (0.65) TSHRALDH1A1FASNFAAHTRPV1
SCHEMBL16098150 0.88 TSHR (0.62) TSHRALDH1A1FASNFAAHTRPV1
SCHEMBL31141323 0.88 TSHR (0.62) TSHRALDH1A1FASNFAAHTRPV1
SCHEMBL3127819 0.88 TSHR (0.62) TSHRALDH1A1FASNFAAHTRPV1
SCHEMBL7057982 0.88 TSHR (0.62) TSHRALDH1A1FASNFAAHTRPV1
SCHEMBL7057750 0.88 TSHR (0.62) TSHRALDH1A1FASNFAAHTRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1858962-B1 FILLED POLYMER COMPOSITIONS MADE FROM INTERPOLYMERS OF ETHYLENE/(A) -OLEFINS AND USES THEREOF DOW GLOBAL TECHNOLOGIES LLC (US) 2018-11-14 EP claimed
CN-101300278-B Polymer composition INEOS MFG BELGIUM NV 2011-08-31 CN claimed
CN-101300278-A Polymer composition INEOS MFG BELGIUM NV (BE) 2008-11-05 CN claimed
CN-1229420-A Improved propylene polymers for oriented films EXXON CHEMICAL PATENTS INC (US) 1999-09-22 CN claimed
EP-0426073-B1 Solid feeding of silane crosslinking agents into extruder UNION CARBIDE CHEM PLASTIC (US) 1997-02-12 EP claimed
CN-116745602-A Method for determining the activity of activated chemically-treated solid oxides in olefin polymerization 切弗朗菲利浦化学公司 2023-09-12 CN disclosed
CN-116099378-B Preparation method and system of hollow fiber membrane type oxygenation membrane 深圳高性能医疗器械国家研究院有限公司 2023-08-15 CN disclosed
CN-116099378-A Preparation method and system of hollow fiber membrane type oxygenation membrane 深圳高性能医疗器械国家研究院有限公司 2023-05-12 CN disclosed
CN-112513193-B Storage stable aqueous dispersions suitable for food contact applications 陶氏环球技术有限责任公司 2023-01-24 CN disclosed
CN-107922669-B Polyethylene powder, process for its preparation and use for rotomoulding 维尔萨利斯股份公司 2022-07-05 CN disclosed
CN-110741039-B Polypropylene composition 博里利斯股份公司 2022-02-18 CN disclosed
CN-108290975-B Production of polyolefins with internal unsaturation using metallocene catalyst systems 埃克森美孚化学专利公司 2021-04-06 CN disclosed
EP-1607774-A1 Phase retardation film and liquid crystal display device including the same Sumitomo Chemical Company, Limited (JP) 2005-12-21 EP disclosed
US-6110549-A HIGH DENSITY POLYETHYLENE AND A LINEAR LOW DENSITY POLYETHYLENE MADE WITH METALLOCENE CATALYST; SEALANT FILM RESISTANT TO WHITENING, HEAT DEFORMATION AFTER BOILING STERILIZATION, AND HAS HIGH IMPACT STRENGTH MITSUI CHEMICALS INC. (JP) 2000-08-29 US disclosed
US-5705584-A COORDINATION CATALYSTS FOR ADDITION POLYMERIZATION OF PROPYLENE MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1998-01-06 US disclosed
US-5331104-A Trimerization of ethylene PHILLIPS PETROLEUM COMPANY (US) 1994-07-19 US disclosed
EP-0365550-B1 COMPOSITION COMPRISING NITROGEN-CONTAINING HYDROCARBON ADDUCTS EXXON CHEMICAL PATENTS INC. (US) 1992-03-11 EP disclosed
US-5047158-A Oil Additives EXXON CHEMICAL PATENTS INC. (US) 1991-09-10 US disclosed
US-4867753-A OIL AND FUEL ADDITIVES EXXON CHEMICAL PATENTS INC. (US) 1989-09-19 US disclosed
EP-0106023-B1 END-CAPPED POLYARYLENE POLYETHERS, ARTICLES MADE THEREFROM AND PROCESS FOR PREPARING SUCH POLYARYLENE POLYETHERS AMOCO CORPORATION (US) 1988-03-30 EP disclosed