Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 15/20 | 1.00 |
| ▸ | PGK1 | P00558 | 5/20 | 0.54 |
| ▸ | GSK3B | P49841 | 1/20 | 0.51 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6306869 | 0.84 | GLP1R (0.72) | GLP1R | |
| SCHEMBL6306899 | 0.80 | GLP1R (1.00) | GLP1R | |
| SCHEMBL6305960 | 0.80 | GLP1R (0.74) | GLP1R | |
| SCHEMBL7845049 | 0.79 | GLP1R (1.00) | GLP1RPGK1 | |
| SCHEMBL2555049 | 0.78 | GLP1R (1.00) | GLP1R | |
| SCHEMBL31673865 | 0.78 | GLP1R (1.00) | GLP1R | |
| SCHEMBL6307213 | 0.78 | GLP1R (1.00) | GLP1R | |
| SCHEMBL6304317 | 0.76 | GLP1R (0.61) | GLP1R | |
| SCHEMBL6303925 | 0.76 | GLP1R (1.00) | GLP1R | |
| SCHEMBL6305727 | 0.76 | GLP1R (0.73) | GLP1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6927214-B1 | Non-peptide GLP-1 agonists | NOVO NORDISK A/S (DK) | 2005-08-09 | — | — | US | claimed |
| US-6927214-B1 | Non-peptide GLP-1 agonists | NOVO NORDISK A/S (DK) | 2005-08-09 | — | — | US | disclosed |