Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 19/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6307733 | 0.88 | CETP (0.49) | CETPSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6304902 | 0.85 | SLC6A2 (0.41) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6305094 | 0.83 | CETP (0.39) | CETP | |
| SCHEMBL6304217 | 0.82 | CETP (0.44) | CETP | |
| SCHEMBL6312494 | 0.81 | CETP (0.44) | CETP | |
| SCHEMBL6307016 | 0.81 | CETP (0.48) | CETPSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6312926 | 0.79 | CETP (0.58) | CETP | |
| SCHEMBL6306960 | 0.78 | CETP (0.45) | CETP | |
| SCHEMBL6304082 | 0.77 | CETP (0.40) | CETPSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6305022 | 0.76 | CETP (0.40) | CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6861561-B2 | Substituted aromatic policyclic tertiary-heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity | G. D. SEARLE & CO. (US) | 2005-03-01 | — | — | US | claimed |