SCHEMBL6304607

SCHEMBL6304607

OCC(c1ccccc1C(F)(F)F)N(Cc1c(F)cccc1C(F)(F)F)c1cccc(OCc2cccc(OC(F)(F)F)c2)c1

nearest known ligand 0.45

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CETP P11597 19/20 0.45
MAOB P27338 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6304605 0.88 CETP (0.46) CETPMAOB
SCHEMBL6304633 0.88 CETP (0.44) CETPMAOB
SCHEMBL6306809 0.87 CETP (0.59) CETP
SCHEMBL6304541 0.87 CETP (0.43) CETPMAOB
SCHEMBL6311999 0.85 CETP (0.46) CETPMAOB
SCHEMBL7076913 0.84 CETP (0.43) CETPMAOB
SCHEMBL6306282 0.81 CETP (0.61) CETP
SCHEMBL6307704 0.80 CETP (0.44) CETPMAOB
SCHEMBL6304806 0.80 CETP (0.44) CETPMAOB
SCHEMBL6312926 0.78 CETP (0.58) CETP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6861561-B2 Substituted aromatic policyclic tertiary-heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity G. D. SEARLE & CO. (US) 2005-03-01 US claimed