Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | THPO | P40225 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL648265 | 0.90 | KMT2A (0.47) | KMT2AHSD17B10USP2MAPTCYP3A4 | |
| SCHEMBL649235 | 0.82 | TLR8 (0.46) | KMT2AHSD17B10USP2MAPTCYP3A4 | |
| SCHEMBL23400347 | 0.81 | KMT2A (0.49) | KMT2AHSD17B10USP2MAPTCYP3A4 | |
| SCHEMBL14586257 | 0.79 | MEN1 (0.65) | KMT2ACYP2C9CYP2C19LMNACYP1A2 | |
| SCHEMBL23401457 | 0.78 | KMT2A (0.56) | KMT2AHSD17B10USP2MAPTCYP3A4 | |
| SCHEMBL6683026 | 0.78 | KMT2A (0.39) | KMT2AHSD17B10USP2MAPTCYP3A4 | |
| SCHEMBL649234 | 0.78 | KMT2A (0.39) | KMT2AHSD17B10USP2MAPTCYP3A4 | |
| SCHEMBL6683019 | 0.78 | CNR2 (0.41) | KMT2AHSD17B10USP2MAPTCYP3A4 | |
| SCHEMBL649236 | 0.78 | CNR1 (0.41) | KMT2AHSD17B10USP2MAPTCYP3A4 | |
| SCHEMBL6617222 | 0.76 | KMT2A (0.38) | KMT2AHSD17B10USP2MAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884815-B1 | High affinity small molecule C5a receptor modulators | NEUROGEN CORPORATION (US) | 2005-04-26 | — | — | US | disclosed |