SCHEMBL6306113

SCHEMBL6306113

CCc1cc(Oc2cccc(N(Cc3cccc(OC(F)(F)C(F)F)c3)CC(O)c3ccc(C(F)(F)F)cc3)c2)ccc1Cl

nearest known ligand 0.77

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CETP P11597 20/20 0.77

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6312341 0.94 CETP (0.76) CETP
SCHEMBL6313544 0.90 CETP (0.77) CETP
SCHEMBL6312348 0.88 CETP (0.78) CETP
SCHEMBL1045843 0.87 CETP (1.00) CETP
SCHEMBL304580 0.87 CETP (1.00) CETP
SCHEMBL29623519 0.87 CETP (1.00) CETP
SCHEMBL6306117 0.87 CETP (0.75) CETP
SCHEMBL6304246 0.87 CETP (0.59) CETP
SCHEMBL6306804 0.86 CETP (0.82) CETP
SCHEMBL7084007 0.86 CETP (0.84) CETP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6861561-B2 Substituted aromatic policyclic tertiary-heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity G. D. SEARLE & CO. (US) 2005-03-01 US claimed
US-6482862-B1 Method of using substituted N-benzyl-N-phenyl aminoalcohols for inhibiting cholesteryl ester transfer protein activity G.D. SEARLE & CO. 2002-11-19 US claimed