Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 4/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 8/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 8/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 8/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 8/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 8/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 8/20 | 0.40 |
| ▸ | CCKBR | P32239 | 2/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6312860 | 0.99 | XIAP (0.42) | XIAPPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL6306461 | 0.85 | BRD4 (0.42) | XIAPPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL6308009 | 0.85 | MEN1 (0.38) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| Hydrochloric Acid SCHEMBL6312630 | 0.84 | NOTCH1 (0.37) | XIAPPSEN1PSEN2APH1BNCSTN | |
| Hydrochloric Acid SCHEMBL6305883 | 0.84 | BRD4 (0.41) | XIAPPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL6305563 | 0.80 | SCN9A (0.47) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL6912415 | 0.75 | PSEN1 (0.56) | XIAPPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL6305912 | 0.75 | BRD4 (0.43) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| Hydrochloric Acid SCHEMBL4411847 | 0.74 | PSEN1 (0.55) | XIAPPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL6300489 | 0.72 | SCN9A (0.52) | XIAPPSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6958330-B1 | Polycyclic α-amino-ε-caprolactams and related compounds | ELAN PHARMACEUTICALS, INC. (US) | 2005-10-25 | — | — | US | disclosed |