Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 10/20 | 0.71 |
| ▸ | HTR2C | P28335 | 4/20 | 0.71 |
| ▸ | CCR3 | P51677 | 4/20 | 0.55 |
| ▸ | HTR1D | P28221 | 1/20 | 0.51 |
| ▸ | HTR1B | P28222 | 1/20 | 0.51 |
| ▸ | ACKR3 | P25106 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6313320 | 1.00 | MCHR1 (0.71) | MCHR1HTR2CCCR3HTR1DHTR1B | |
| SCHEMBL6312700 | 0.95 | MCHR1 (0.63) | MCHR1HTR2CACKR3NPC1RAB9A | |
| SCHEMBL6314146 | 0.95 | MCHR1 (0.78) | MCHR1HTR2CCCR3HTR1DHTR1B | |
| SCHEMBL6312554 | 0.91 | MCHR1 (0.69) | MCHR1HTR2CCCR3HTR1DHTR1B | |
| SCHEMBL6304919 | 0.91 | MCHR1 (0.69) | MCHR1HTR2CCCR3HTR1DHTR1B | |
| SCHEMBL6313332 | 0.91 | MCHR1 (0.71) | MCHR1HTR2CCCR3HTR1DHTR1B | |
| SCHEMBL6306094 | 0.91 | MCHR1 (0.58) | MCHR1HTR2CACKR3NPC1RAB9A | |
| SCHEMBL6305331 | 0.90 | MCHR1 (0.59) | MCHR1HTR2CCCR3ACKR3 | |
| SCHEMBL6304577 | 0.90 | MCHR1 (0.59) | MCHR1HTR2CCCR3ACKR3 | |
| SCHEMBL6312426 | 0.90 | MCHR1 (0.62) | MCHR1HTR2CCCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6930185-B2 | Melanin-concentrating hormone antagonist | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2005-08-16 | — | — | US | disclosed |
| US-20040077628-A1 | Melanin-concentrating hormone antagonist | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-04-22 | — | — | US | disclosed |
| EP-1285651-A1 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2003-02-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040077628-A1 | Melanin-concentrating hormone antagonist | MCHR1, MC1R, MCHR2 | MCHR1 1/4885HTR2C 107/4885CCR3 1149/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.