Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 17/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 15/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 10/20 | 0.44 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6188615 | 0.99 | SLC6A2 (0.54) | SLC6A2SLC6A4SLC6A3YTHDC1GBA1 | |
| Hydrochloric Acid SCHEMBL6307333 | 0.99 | SLC6A2 (0.54) | SLC6A2SLC6A4SLC6A3YTHDC1GBA1 | |
| SCHEMBL2877349 | 0.84 | SLC6A2 (0.73) | SLC6A2SLC6A4SLC6A3YTHDC1GBA1 | |
| SCHEMBL6393397 | 0.78 | SLC6A2 (0.49) | SLC6A2SLC6A4SLC6A3GBA1 | |
| SCHEMBL5428676 | 0.75 | SLC6A2 (0.70) | SLC6A2SLC6A4SLC6A3GBA1 | |
| SCHEMBL24424448 | 0.75 | SLC6A2 (0.60) | SLC6A2SLC6A4SLC6A3YTHDC1GBA1 | |
| SCHEMBL25090743 | 0.75 | SLC6A2 (0.60) | SLC6A2SLC6A4SLC6A3YTHDC1GBA1 | |
| SCHEMBL29585236 | 0.75 | SLC6A2 (0.60) | SLC6A2SLC6A4SLC6A3YTHDC1GBA1 | |
| Hydrochloric Acid SCHEMBL15012232 | 0.74 | SLC6A2 (0.57) | SLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL15012233 | 0.74 | SLC6A2 (0.57) | SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050209274-A1 | Antagonists of melanin concentrating hormone effects on the melanin concentrating hormone receptor | ABOTT LABORATORIES | 2005-09-22 | — | — | US | disclosed |
| US-20050187387-A1 | Antagonists of melanin concentrating hormone effects on the melanin concentrating hormone receptor | ABBOTT LABORATORIES | 2005-08-25 | — | — | US | disclosed |
| US-6921821-B2 | Antagonists of melanin concentrating hormone receptor | ABBOTT LABORATORIES (US) | 2005-07-26 | — | — | US | disclosed |
| US-20040106645-A1 | Antagonists of melanin concentrating hormone receptor | MILLENNIUM PHARMACEUTICALS, INC. | 2004-06-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050209274-A1 | Antagonists of melanin concentrating hormone effects on the melanin concentrating hormone receptor | MCHR1, MCHR2, MC1R | SLC6A2 109/4885SLC6A4 151/4885SLC6A3 61/4885 |
| US-20040106645-A1 | Antagonists of melanin concentrating hormone receptor | MCHR1, MCHR2, MC1R | SLC6A2 1013/4885SLC6A4 1353/4885SLC6A3 1094/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.