Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGT2B7 | P16662 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP7 | P09237 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | MMP12 | P39900 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6301703 | 0.89 | UGT2B7 (0.48) | UGT2B7MEN1CYP1A2KMT2AAOC3 | |
| SCHEMBL19003721 | 0.82 | UGT2B7 (0.48) | UGT2B7MEN1CYP1A2KMT2AAOC3 | |
| SCHEMBL6008487 | 0.82 | UGT2B7 (0.52) | UGT2B7MEN1CYP1A2KMT2AAOC3 | |
| SCHEMBL31036064 | 0.81 | MEN1 (0.57) | UGT2B7MEN1CYP1A2KMT2AAOC3 | |
| SCHEMBL6317871 | 0.81 | MEN1 (0.57) | UGT2B7MEN1CYP1A2KMT2AAOC3 | |
| SCHEMBL6301619 | 0.79 | UGT2B7 (0.46) | UGT2B7MMP1MMP7ACEMMP12 | |
| SCHEMBL15345330 | 0.79 | SLC2A1 (0.46) | UGT2B7MEN1CYP1A2KMT2AAOC3 | |
| SCHEMBL10582738 | 0.79 | UGT2B7 (0.46) | UGT2B7MEN1CYP1A2KMT2AAOC3 | |
| SCHEMBL31036013 | 0.79 | SLC2A1 (0.46) | UGT2B7MEN1CYP1A2KMT2AAOC3 | |
| SCHEMBL7496718 | 0.79 | UGT2B7 (0.46) | UGT2B7MEN1CYP1A2KMT2AAOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6869950-B1 | Benzimidazole derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-03-22 | — | — | US | disclosed |
| EP-1142880-A1 | BENZIMIDAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-10-10 | — | — | EP | disclosed |