Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.53 |
| ▸ | SIRT2 | Q8IXJ6 | 6/20 | 0.45 |
| ▸ | PDE2A | O00408 | 2/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6301246 | 0.90 | PPARG (0.56) | PPARGTRPV1 | |
| SCHEMBL6307861 | 0.84 | PPARG (0.56) | PPARGSIRT2PDE2APDE10AALDH1A1 | |
| SCHEMBL6301120 | 0.84 | PPARG (0.78) | PPARGTRPV1 | |
| SCHEMBL6308646 | 0.83 | PPARG (0.56) | PPARGSIRT2PDE2APDE10ASIRT1 | |
| SCHEMBL6309536 | 0.83 | PPARG (0.56) | PPARGSIRT2PDE2APDE10AALDH1A1 | |
| SCHEMBL6308739 | 0.83 | PPARG (0.56) | PPARGSIRT2PDE2APDE10AALDH1A1 | |
| SCHEMBL6301191 | 0.83 | PPARG (0.55) | PPARGSIRT2PDE2APDE10ASIRT1 | |
| SCHEMBL6304029 | 0.82 | PPARG (0.55) | PPARGSIRT2PDE2APDE10ASIRT1 | |
| SCHEMBL6307980 | 0.82 | PPARG (0.55) | PPARGSIRT2PDE2APDE10ASIRT1 | |
| SCHEMBL6173254 | 0.82 | PPARG (0.62) | PPARGSIRT2PDE2APDE10ASIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6869950-B1 | Benzimidazole derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-03-22 | — | — | US | disclosed |
| EP-1142880-A1 | BENZIMIDAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-10-10 | — | — | EP | disclosed |