⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL28822792 | 0.97 | — | — | |
| Water SCHEMBL2842215 | 0.97 | — | — | |
| SCHEMBL28193329 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL28193874 | 0.73 | — | — | |
| SCHEMBL8163324 | 0.72 | MEN1 (0.35) | — | |
| SCHEMBL926283 | 0.72 | — | — | |
| Water SCHEMBL10786849 | 0.71 | — | — | |
| SCHEMBL20472038 | 0.69 | — | — | |
| SCHEMBL9911186 | 0.69 | MEN1 (0.39) | — | |
| Hydrochloric Acid SCHEMBL749078 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107708810-A | Conjugates of cysteine engineered antibodies | 伊缪诺金公司 | 2018-02-16 | — | — | CN | disclosed |
| CN-107335061-A | Cytotoxic benzodiazepine * derivatives | 伊缪诺金公司 | 2017-11-10 | — | — | CN | disclosed |
| CN-107050468-A | The preparation method of conjugate | 伊缪诺金公司 | 2017-08-18 | — | — | CN | disclosed |
| CN-103687623-B | Cytotoxic benzodiazepine derivatives | 伊缪诺金公司 | 2017-06-09 | — | — | CN | disclosed |
| CN-101880397-B | Cross linking polymer and preparation method thereof | CHANGCHUN APPLIED CHEMISTRY | 2012-06-27 | — | — | CN | disclosed |
| CN-101880397-A | Cross linking polymer and preparation method thereof | CHANGCHUN APPLIED CHEMISTRY | 2010-11-10 | — | — | CN | disclosed |
| US-6943253-B2 | 6-phenylpyrrolopyrimidinedione derivatives | ALMIRALL PRODESFARMA S.A. (ES) | 2005-09-13 | — | — | US | disclosed |
| EP-1286997-B1 | 6-PHENYLPYRROLOPYRIMIDINEDIONE DERIVATIVES | ALMIRALL PRODESFARMA SA (ES) | 2004-08-18 | — | — | EP | disclosed |
| US-20030232838-A1 | Nitrogen compounds such as 3-Methyl-6-(5-(4-methylpiperazine-1-sulphonyl)-2-propoxyphenyl)-1-propyl-1,5-dihydropyrrolo(3,2-d)pyrimidine-2,4-dione, used for prophylaxis of cardiovascular disorders | PARALLEL WIRELESS, INC. | 2003-12-18 | — | — | US | disclosed |