Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 5/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | BCL2L1 | Q07817 | 10/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 10/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6135129 | 0.89 | PPARG (0.56) | PTGER4PPARGBCL2L1MCL1 | |
| SCHEMBL1160104 | 0.85 | BCL2L1 (0.48) | PTGER4PPARGBCL2L1MCL1 | |
| SCHEMBL6303464 | 0.84 | PPARG (0.63) | PTGER4PPARG | |
| SCHEMBL6308456 | 0.84 | PPARG (0.49) | PTGER4PPARG | |
| SCHEMBL6303650 | 0.81 | PDE2A (0.49) | PTGER4PPARGMAPT | |
| SCHEMBL7649091 | 0.81 | PPARG (0.53) | PTGER4PPARGBCL2L1MCL1 | |
| SCHEMBL1160331 | 0.80 | PPARG (0.57) | PTGER4PPARGTDP1TP53MAPT | |
| SCHEMBL7652179 | 0.79 | PPARG (0.55) | PPARGTDP1MAPT | |
| SCHEMBL7654833 | 0.79 | PPARG (0.52) | PPARGBCL2L1MCL1TP53MAPT | |
| SCHEMBL7654248 | 0.79 | PPARG (0.52) | PPARGBCL2L1MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1142880-A1 | BENZIMIDAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-10-10 | — | — | EP | claimed |
| US-6869950-B1 | Benzimidazole derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-03-22 | — | — | US | disclosed |
| EP-1142880-A1 | BENZIMIDAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-10-10 | — | — | EP | disclosed |