Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 15/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL630636 | 0.85 | AR (0.46) | ARPGR | |
| SCHEMBL3806561 | 0.85 | AR (0.46) | ARPGR | |
| SCHEMBL629676 | 0.84 | AR (0.50) | ARPGRHDAC1 | |
| SCHEMBL890915 | 0.83 | AR (0.49) | ARPGRHDAC1 | |
| SCHEMBL629351 | 0.74 | AR (0.49) | ARPGR | |
| SCHEMBL1435047 | 0.73 | AR (0.71) | ARHDAC1 | |
| SCHEMBL629322 | 0.73 | AR (0.52) | ARPGR | |
| SCHEMBL630341 | 0.72 | AR (0.48) | ARPGR | |
| SCHEMBL629446 | 0.72 | AR (0.46) | ARPGRHDAC1 | |
| SCHEMBL891330 | 0.72 | AR (0.44) | ARPGRHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2419410-A1 | IMIDAZOLIDINE-2,4-DIONE DERIVATIVES, AND USE THEREOF AS A CANCER DRUG | IPSEN PHARMA S.A.S. (FR) | 2012-02-22 | — | — | EP | disclosed |
| WO-2010119193-A1 | IMIDAZOLIDINE-2,4-DIONE DERIVATIVES, AND USE THEREOF AS A CANCER DRUG | IPSEN PHARMA S.A.S. (FR) | 2010-10-21 | — | — | WO | disclosed |