Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAL | P20701 | 20/20 | 0.39 |
| ▸ | ITGB2 | P05107 | 19/20 | 0.39 |
| ▸ | ICAM1 | P05362 | 19/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6311930 | 0.84 | ITGAL (0.52) | ITGALITGB2ICAM1 | |
| SCHEMBL6312906 | 0.72 | ITGB2 (0.36) | ITGALITGB2ICAM1 | |
| SCHEMBL6198868 | 0.70 | ITGAL (0.48) | ITGALITGB2ICAM1 | |
| SCHEMBL6196026 | 0.69 | ITGAL (0.47) | ITGALITGB2ICAM1 | |
| SCHEMBL6197945 | 0.68 | ITGAL (0.44) | ITGALITGB2ICAM1 | |
| SCHEMBL6200024 | 0.68 | ITGB2 (0.37) | ITGALITGB2ICAM1 | |
| SCHEMBL6195217 | 0.68 | ITGAL (0.48) | ITGALITGB2ICAM1 | |
| SCHEMBL6198059 | 0.68 | ITGAL (0.46) | ITGALITGB2ICAM1 | |
| SCHEMBL6196455 | 0.68 | ITGAL (0.41) | ITGALITGB2ICAM1 | |
| SCHEMBL6199269 | 0.68 | ITGAL (0.49) | ITGALITGB2ICAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6867203-B2 | Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds | ABBOTT LABORATORIES (US) | 2005-03-15 | — | — | US | disclosed |
| US-20040116518-A1 | Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds | ABBOTT LABORATORIES | 2004-06-17 | — | — | US | disclosed |