SCHEMBL6311116

SCHEMBL6311116

CC(C)N(C)c1nc2cc(Cl)c(Cl)cc2nc1S(C)(=O)=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GLP1R P43220 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6303710 0.85 GLP1R (1.00) GLP1R
SCHEMBL6305810 0.80 GLP1R (1.00) GLP1R
SCHEMBL6307427 0.76 GLP1R (1.00) GLP1R
SCHEMBL6307213 0.75 GLP1R (1.00) GLP1R
SCHEMBL6307043 0.74 GLP1R (0.68) GLP1R
SCHEMBL6304022 0.73 GLP1R (0.66) GLP1R
SCHEMBL6304341 0.72 GLP1R (0.60) GLP1R
SCHEMBL6304035 0.72 GLP1R (1.00) GLP1R
SCHEMBL6304227 0.72 GLP1R (0.66) GLP1R
SCHEMBL6307940 0.71 GLP1R (1.00) GLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6927214-B1 Non-peptide GLP-1 agonists NOVO NORDISK A/S (DK) 2005-08-09 US claimed
US-6927214-B1 Non-peptide GLP-1 agonists NOVO NORDISK A/S (DK) 2005-08-09 US disclosed
EP-1147094-A1 NON-PEPTIDE GLP-1 AGONISTS NOVO NORDISK A/S (DK) 2001-10-24 EP disclosed
WO-2000042026-A1 NON-PEPTIDE GLP-1 AGONISTS NOVO NORDISK A/S (DK) 2000-07-20 WO disclosed