Di(Hydroxyethyl)Ether

Di(Hydroxyethyl)Ether

SCHEMBL631146

C=C(C)COCC(=C)C.OCCOCCO

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.53
MAPK1 P28482 2/20 0.53
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
ALDH1A1 P00352 2/20 0.43
THRB P10828 1/20 0.39
HTT P42858 1/20 0.39
MAPT P10636 1/20 0.39
HSD17B10 Q99714 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
USP2 O75604 1/20 0.30
LMNA P02545 1/20 0.30
CYP3A4 P08684 1/20 0.30
CASP1 P29466 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
SLCO1B3 Q9NPD5 1/20 0.30
SLCO1B1 Q9Y6L6 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8076735 0.92 MEN1 (0.55) TSHRMAPK1MEN1KMT2AALDH1A1
SCHEMBL8536736 0.92 MEN1 (0.55) TSHRMAPK1MEN1KMT2AALDH1A1
SCHEMBL8072378 0.92 MEN1 (0.55) TSHRMAPK1MEN1KMT2AALDH1A1
SCHEMBL18843006 0.92 MEN1 (0.55) TSHRMAPK1MEN1KMT2AALDH1A1
SCHEMBL1326296 0.92
Ethylene Glycol SCHEMBL631461 0.86 HSD17B10 (0.35) TSHRMAPK1ALDH1A1HSD17B10TDP1
Di(Hydroxyethyl)Ether SCHEMBL12541322 0.85 TSHR (0.48) TSHRMAPK1MEN1KMT2AALDH1A1
Di(Hydroxyethyl)Ether SCHEMBL8151639 0.83 TSHR (0.59) TSHRMAPK1MEN1KMT2AALDH1A1
SCHEMBL608739 0.83
1,4-Butanediol SCHEMBL871698 0.81 SMN1; SMN2 (0.36) TSHRMEN1KMT2AALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5225473-A For bioelectrodes MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-07-06 US claimed
US-5153284-A Suspension polymerization using dispersant which is mixture of partially saponified polyvinyl alcohol, cellulose ethers and crosslinked carboxylic polymer SHIN-ETSU CHEMICAL CO., LTD. (JP) 1992-10-06 US claimed
US-4536206-A CROSSLINKED HIGH MOLECULAR WEIGHT CARBOXYLIC CONTAINING POLYMER AND WATER, NONPHYTOTOXIC, NONTOXIC WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 1985-08-20 US claimed
EP-2152771-B2 PRODUCTION METHOD OF UNSATURATED (POLY)ALKYLENE GLYCOL ETHER MONOMER AND PRODUCTION METHOD OF (POLY)ALKYLENE GLYCOL CHAIN-CONTAINING POLYMER NIPPON CATALYTIC CHEM IND (JP) 2021-03-10 EP disclosed
EP-2552497-B1 METHOD OF STERILIZATION OF WOUND DRESSINGS 3M INNOVATIVE PROPERTIES CO (US) 2021-01-13 EP disclosed
EP-2259803-B2 DEVICE FOR PROMOTION OF HEMOSTASIS AND/OR WOUND HEALING FERROSAN MEDICAL DEVICES AS (DK) 2019-03-13 EP disclosed
US-9533069-B2 Device for promotion of hemostasis and/or wound healing Ferrosan Medical Devices A/S (DK) 2017-01-03 US disclosed
EP-1020195-B2 Wound dressing JENTEC INC (US) 2016-09-14 EP disclosed
US-9439809-B2 Method of sterilization of wound dressings 3M INNOVATIVE PROPERTIES COMPANY (US) 2016-09-13 US disclosed
EP-2152771-B1 PRODUCTION METHOD OF UNSATURATED (POLY)ALKYLENE GLYCOL ETHER MONOMER AND PRODUCTION METHOD OF (POLY)ALKYLENE GLYCOL CHAIN-CONTAINING POLYMER NIPPON CATALYTIC CHEM IND (JP) 2016-09-07 EP disclosed
US-20160213891-A1 Medical Dilation Element ZAMORE, ALAN 2016-07-28 US disclosed
EP-0318183-B1 PRESSURE-SENSITIVE MEDICAL SEALANT MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-08-11 EP disclosed
US-5225473-A For bioelectrodes MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-07-06 US disclosed
EP-0507878-A1 COMPOSITE OF A DISPERSED GEL IN AN ADHESIVE MATRIX AND METHOD FOR PREPARING SAME. MINNESOTA MINING & MFG (US) 1992-10-14 EP disclosed
US-5153284-A Suspension polymerization using dispersant which is mixture of partially saponified polyvinyl alcohol, cellulose ethers and crosslinked carboxylic polymer SHIN-ETSU CHEMICAL CO., LTD. (JP) 1992-10-06 US disclosed
WO-1991009633-A1 COMPOSITE OF A DISPERSED GEL IN AN ADHESIVE MATRIX AND METHOD FOR PREPARING SAME MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-07-11 WO disclosed
US-4931282-A Pressure-sensitive medical sealant MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1990-06-05 US disclosed
US-4846185-A FOR ELECTROCARDIOGRAMS; CORROSION RESISTANT MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-07-11 US disclosed
EP-0322098-A1 Pressure-sensitive adhesives and bioelectrodes constructed with the adhesive MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-06-28 EP disclosed
EP-0318183-A2 Pressure-sensitive medical sealant MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-05-31 EP disclosed