Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 20/20 | 0.59 |
| ▸ | ICAM1 | P05362 | 20/20 | 0.59 |
| ▸ | ITGAL | P20701 | 20/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5830377 | 0.90 | ITGB2 (0.62) | ITGB2ICAM1ITGAL | |
| SCHEMBL6309800 | 0.88 | ITGB2 (0.58) | ITGB2ICAM1ITGAL | |
| SCHEMBL6309906 | 0.86 | ITGB2 (0.72) | ITGB2ICAM1ITGAL | |
| SCHEMBL6198403 | 0.82 | ITGB2 (0.54) | ITGB2ICAM1ITGAL | |
| SCHEMBL6197108 | 0.82 | ITGB2 (0.58) | ITGB2ICAM1ITGAL | |
| SCHEMBL6317156 | 0.81 | ITGB2 (0.66) | ITGB2ICAM1ITGAL | |
| SCHEMBL6198401 | 0.80 | ITGB2 (0.54) | ITGB2ICAM1ITGAL | |
| SCHEMBL6310393 | 0.80 | ITGAL (0.58) | ITGB2ICAM1ITGAL | |
| SCHEMBL6312299 | 0.76 | ITGB2 (0.82) | ITGB2ICAM1ITGAL | |
| SCHEMBL6199684 | 0.75 | ITGB2 (0.56) | ITGB2ICAM1ITGAL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6878700-B1 | Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds | ABBOTT LABORATORIES (US) | 2005-04-12 | — | — | US | claimed |
| US-6878700-B1 | Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds | ABBOTT LABORATORIES (US) | 2005-04-12 | — | — | US | disclosed |
| US-6867203-B2 | Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds | ABBOTT LABORATORIES (US) | 2005-03-15 | — | — | US | disclosed |
| US-20040116518-A1 | Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds | ABBOTT LABORATORIES | 2004-06-17 | — | — | US | disclosed |