Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | USP2 | O75604 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylonitrile SCHEMBL9562514 | 0.85 | TSHR (0.75) | TSHRMAPTUSP2CYP3A4SMN1; SMN2 | |
| Acetic Acid Isobutyl Ester SCHEMBL382890 | 0.84 | TSHR (0.48) | TSHRMAPTUSP2CYP3A4SMN1; SMN2 | |
| Acetic Acid Isobutyl Ester SCHEMBL18229923 | 0.83 | — | — | |
| Acrylonitrile SCHEMBL11816648 | 0.83 | TSHR (0.78) | TSHRMAPTCYP3A4SMN1; SMN2ALDH1A1 | |
| Acetic Acid Isobutyl Ester SCHEMBL6360200 | 0.81 | TSHR (0.60) | TSHRMAPTUSP2CYP3A4SMN1; SMN2 | |
| Acetic Acid Isobutyl Ester SCHEMBL28489463 | 0.81 | TSHR (0.60) | TSHRMAPTUSP2CYP3A4SMN1; SMN2 | |
| Acetic Acid Isobutyl Ester SCHEMBL22678 | 0.81 | — | — | |
| Acetic Acid Isobutyl Ester SCHEMBL27572527 | 0.81 | TSHR (0.58) | TSHRMAPTUSP2CYP3A4SMN1; SMN2 | |
| Acetic Acid Isobutyl Ester SCHEMBL27530275 | 0.80 | TSHR (0.61) | TSHRMAPTUSP2CYP3A4SMN1; SMN2 | |
| Acetic Acid Isobutyl Ester SCHEMBL28759612 | 0.79 | TSHR (0.52) | TSHRMAPTUSP2CYP3A4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6852858-B2 | Process for purifying N-[3-(3-cyanopyrazolo[1,5-a]pyrimidin-7-yl)phenyl]-N-ethylacetamide (zaleplon) and crystalline forms of zaleplon accessible with the process | BIOGAL GYOGYSZERGYAR RT. (HU) | 2005-02-08 | — | — | US | claimed |