Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.49 |
| ▸ | PDE5A | O76074 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15156200 | 0.84 | SMN1; SMN2 (0.55) | SMN1; SMN2ALDH1A1KDM4ENPC1MAPT | |
| SCHEMBL11410724 | 0.84 | SMN1; SMN2 (0.61) | CYP3A4CYP2C19CYP1A2SMN1; SMN2ALDH1A1 | |
| SCHEMBL14172936 | 0.84 | PDE5A (0.59) | CYP3A4CYP2C19CYP1A2SMN1; SMN2ALDH1A1 | |
| SCHEMBL5009820 | 0.83 | MAPT (0.62) | CYP3A4CYP2C19CYP1A2SMN1; SMN2ALDH1A1 | |
| SCHEMBL4442984 | 0.82 | HSP90AA1 (0.57) | CYP3A4CYP2C19CYP1A2SMN1; SMN2ALDH1A1 | |
| SCHEMBL13330092 | 0.81 | CYP1A2 (0.57) | CYP3A4CYP2C19CYP1A2SMN1; SMN2ALDH1A1 | |
| SCHEMBL15400405 | 0.81 | CYP3A4 (0.68) | CYP3A4CYP2C19CYP1A2SMN1; SMN2ALDH1A1 | |
| SCHEMBL18918544 | 0.81 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1NPC1MAPTLMNA | |
| SCHEMBL23223762 | 0.80 | SMN1; SMN2 (0.49) | SMN1; SMN2ALDH1A1NPC1MAPTLMNA | |
| SCHEMBL2276760 | 0.79 | HPGD (0.56) | SMN1; SMN2ALDH1A1HPGDMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050014810-A1 | Use of substituted 2 phenylbenzimidazoles as medicaments | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014810-A1 | Use of substituted 2 phenylbenzimidazoles as medicaments | GLP1R, GIPR, GCGR | CYP3A4 439/4885CYP2C19 462/4885CYP1A2 624/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.