Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 13/20 | 0.57 |
| ▸ | ITGA5 | P08648 | 4/20 | 0.57 |
| ▸ | ITGA4 | P13612 | 6/20 | 0.54 |
| ▸ | ITGB7 | P26010 | 3/20 | 0.54 |
| ▸ | ITGAV | P06756 | 5/20 | 0.51 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GPR34 | Q9UPC5 | 2/20 | 0.45 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.45 |
| ▸ | FKBP4 | Q02790 | 1/20 | 0.44 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL631365 | 1.00 | ITGB1 (0.57) | ITGB1ITGA5ITGA4ITGB7ITGAV | |
| SCHEMBL629713 | 1.00 | ITGB1 (0.57) | ITGB1ITGA5ITGA4ITGB7ITGAV | |
| SCHEMBL629712 | 1.00 | ITGB1 (0.57) | ITGB1ITGA5ITGA4ITGB7ITGAV | |
| SCHEMBL630558 | 0.92 | ITGB1 (0.53) | ITGB1ITGA5ITGA4ITGB7ITGAV | |
| SCHEMBL630557 | 0.92 | ITGB1 (0.53) | ITGB1ITGA5ITGA4ITGB7ITGAV | |
| SCHEMBL630332 | 0.91 | ITGB1 (0.49) | ITGB1ITGA5ITGA4ITGB7ITGAV | |
| SCHEMBL630333 | 0.91 | ITGB1 (0.49) | ITGB1ITGA5ITGA4ITGB7ITGAV | |
| SCHEMBL5173099 | 0.91 | ITGB1 (0.49) | ITGB1ITGA5ITGA4ITGB7ITGAV | |
| SCHEMBL629802 | 0.89 | KCNQ1 (0.48) | ITGB1ITGA5ITGA4ITGB7ITGAV | |
| SCHEMBL8268315 | 0.89 | KCNQ1 (0.48) | ITGB1ITGA5ITGA4ITGB7ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778637-B1 | FKBP-binding composition and pharmaceutical use thereof | AVENTIS PHARMA INC (US) | 2012-02-22 | — | — | EP | disclosed |
| EP-1778637-A2 | FKBP BINDING COMPOSITION AND PHARMACEUTICAL USE THEREOF | Aventis Pharmaceuticals, Inc. (US) | 2007-05-02 | — | — | EP | disclosed |
| WO-2006012256-A2 | FKBP BINDING COMPOSITION AND PHARMACEUTICAL USE THEREOF | AVENTIS PHARMACEUTICALS INC. (US) | 2006-02-02 | — | — | WO | disclosed |