SCHEMBL6313898

SCHEMBL6313898

CSOP(=O)(Cl)OCC(F)(F)F

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9818237 0.80 SMN1; SMN2 (0.40) SMN1; SMN2
SCHEMBL9659688 0.72
SCHEMBL10934795 0.71 TP53 (0.43) SMN1; SMN2
SCHEMBL11421035 0.69 CYP3A4 (0.47) SMN1; SMN2
SCHEMBL1009556 0.69 SMN1; SMN2 (0.39) SMN1; SMN2
SCHEMBL31050159 0.67 SMN1; SMN2 (0.38) SMN1; SMN2
SCHEMBL31050154 0.67 SMN1; SMN2 (0.38) SMN1; SMN2
SCHEMBL31449606 0.67 SMN1; SMN2 (0.32) SMN1; SMN2
SCHEMBL575164 0.66 SMN1; SMN2 (0.36) SMN1; SMN2
SCHEMBL576070 0.66 SMN1; SMN2 (0.36) SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050164885-A1 Alkyl dihalogenated phenyl-substituted ketoenols useful as pesticides and herbicides BAYER AG (DE) 2005-07-28 US disclosed
US-6858741-B2 Alkyl-dihalogenated phenyl-substituted ketoenols useful as pesticides and herbicides BAYER AKTIENGESELLSCHAFT (DE) 2005-02-22 US disclosed
US-20030199572-A1 Alkyl-dihalogenophenyl-substituted ketoenols LIEB FOLKER (DE) 2003-10-23 US disclosed
US-6380246-B1 FOR COMBATING PESTS AND WEEDS BAYER AKTIENGESELLSCHAFT (DE) 2002-04-30 US disclosed
US-6316486-B1 FOR COMBATING PESTS AND WEED BAYER AKTIENGESELLSCHAFT (DE) 2001-11-13 US disclosed
US-5811374-A INSECTICIDES; ACARICIDES; HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1998-09-22 US disclosed
US-5677449-A PESTICIDES BAYER AKTIENGESELLSCHAFT (DE) 1997-10-14 US disclosed
US-5616536-A INSECTICIDES, MITICIDES, HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1997-04-01 US disclosed
US-5602078-A POSSESS HERBICIDAL AND PESTICIDAL ACTIVITY BAYER AKTIENGESELLSCHAFT (DE) 1997-02-11 US disclosed
US-5589469-A INSECTICIDES, MITICIDES OR HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1996-12-31 US disclosed
US-5567671-A HERBICIDES, PESTICIDES BAYER AKTIENGESELLSCHAFT (DE) 1996-10-22 US disclosed
US-5504057-A HERBICIDES; PESTICIDES BAYER AKTIENGESELLSCHAFT (DE) 1996-04-02 US disclosed
US-5462913-A Pesticides, insecticides, miticides, herbicides BAYER AKTIENGESELLSCHAFT (DE) 1995-10-31 US disclosed
US-5225434-A PESTICIDAL AND HERBICIDAL POLYCYCLIC 3-ARYL-PYRROLIDINE-2,4-DIONE DERIVATIVES BAYER AKTIENGESELLSCHAFT (DE) 1993-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050164885-A1 Alkyl dihalogenated phenyl-substituted ketoenols useful as pesticides and herbicides DDT, CYP8B1, PAOX SMN1; SMN2 4806/4885
US-20030199572-A1 Alkyl-dihalogenophenyl-substituted ketoenols CYP2E1, CYP8B1, CYP24A1 SMN1; SMN2 4464/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.