Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 13/20 | 0.67 |
| ▸ | ACHE | P22303 | 4/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.50 |
| ▸ | BCHE | P06276 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6188990 | 0.94 | MCHR1 (0.65) | MCHR1ACHEKCNH2BCHEMAOB | |
| Trifluoroacetic Acid SCHEMBL6208466 | 0.94 | MCHR1 (0.65) | MCHR1ACHEKCNH2BCHEMAOB | |
| Trifluoroacetic Acid SCHEMBL6188612 | 0.93 | MCHR1 (0.69) | MCHR1ACHEKCNH2BCHEMAOB | |
| SCHEMBL6308290 | 0.93 | MCHR1 (0.76) | MCHR1ACHEKCNH2 | |
| Trifluoroacetic Acid SCHEMBL6207712 | 0.92 | MCHR1 (0.66) | MCHR1ACHEKCNH2BCHEMAOB | |
| Trifluoroacetic Acid SCHEMBL6188879 | 0.90 | MCHR1 (0.66) | MCHR1ACHEKCNH2BCHEMAOB | |
| Trifluoroacetic Acid SCHEMBL6210165 | 0.90 | MCHR1 (0.66) | MCHR1ACHEKCNH2BCHEMAOB | |
| Trifluoroacetic Acid SCHEMBL6208550 | 0.90 | MCHR1 (0.66) | MCHR1ACHEKCNH2BCHEMAOB | |
| Trifluoroacetic Acid SCHEMBL6208461 | 0.90 | MCHR1 (0.64) | MCHR1ACHEKCNH2BCHEMAOB | |
| Trifluoroacetic Acid SCHEMBL6207368 | 0.90 | MCHR1 (0.67) | MCHR1ACHEKCNH2BCHEMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6921821-B2 | Antagonists of melanin concentrating hormone receptor | ABBOTT LABORATORIES (US) | 2005-07-26 | — | — | US | disclosed |
| US-20040106645-A1 | Antagonists of melanin concentrating hormone receptor | MILLENNIUM PHARMACEUTICALS, INC. | 2004-06-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040106645-A1 | Antagonists of melanin concentrating hormone receptor | MCHR1, MCHR2, MC1R | MCHR1 1/4885ACHE 3307/4885KCNH2 2839/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.