Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 5/20 | 0.65 |
| ▸ | HTR2C | P28335 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | DRD2 | P14416 | 2/20 | 0.53 |
| ▸ | DRD4 | P21917 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
| ▸ | FAAH | O00519 | 5/20 | 0.51 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.51 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6304597 | 1.00 | MCHR1 (0.65) | MCHR1HTR2CSMN1; SMN2NLRP3MAPT | |
| SCHEMBL6305313 | 0.95 | MCHR1 (0.70) | MCHR1HTR2CSMN1; SMN2NLRP3MAPT | |
| SCHEMBL6304593 | 0.95 | MCHR1 (0.70) | MCHR1HTR2CSMN1; SMN2MAPTTP53 | |
| SCHEMBL2925998 | 0.91 | MCHR1 (0.77) | MCHR1HTR2CSMN1; SMN2NLRP3MAPT | |
| SCHEMBL6305166 | 0.91 | MCHR1 (0.77) | MCHR1HTR2CSMN1; SMN2MAPTTP53 | |
| SCHEMBL6312214 | 0.91 | MCHR1 (0.68) | MCHR1HTR2CSMN1; SMN2NLRP3MAPT | |
| SCHEMBL6305320 | 0.91 | MCHR1 (0.68) | MCHR1HTR2CSMN1; SMN2NLRP3MAPT | |
| SCHEMBL6305203 | 0.91 | MCHR1 (0.65) | MCHR1HTR2CSMN1; SMN2NLRP3MAPT | |
| SCHEMBL6314150 | 0.91 | MCHR1 (0.65) | MCHR1HTR2CSMN1; SMN2NLRP3MAPT | |
| SCHEMBL6314183 | 0.91 | MCHR1 (0.65) | MCHR1HTR2CMAPTTP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6930185-B2 | Melanin-concentrating hormone antagonist | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2005-08-16 | — | — | US | disclosed |
| US-20040077628-A1 | Melanin-concentrating hormone antagonist | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-04-22 | — | — | US | disclosed |
| EP-1285651-A1 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2003-02-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040077628-A1 | Melanin-concentrating hormone antagonist | MCHR1, MC1R, MCHR2 | MCHR1 1/4885HTR2C 107/4885SMN1; SMN2 4079/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.