⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2231928 | 0.74 | — | — | |
| SCHEMBL1973430 | 0.72 | — | — | |
| SCHEMBL27963072 | 0.72 | — | — | |
| SCHEMBL17607445 | 0.72 | — | — | |
| SCHEMBL27686655 | 0.70 | — | — | |
| SCHEMBL27936409 | 0.70 | — | — | |
| SCHEMBL591726 | 0.70 | — | — | |
| SCHEMBL17607768 | 0.70 | — | — | |
| SCHEMBL17607650 | 0.68 | — | — | |
| SCHEMBL8746343 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050238616-A1 | Compositions for treatment of central nervous system neoplasms, and methods of making and using the same | GUILFORD PHARMACEUTICALS, INC. (US) | 2005-10-27 | — | — | US | disclosed |
| US-20040197301-A1 | Hybrid polymers and methods of making the same | EISAI INC. | 2004-10-07 | — | — | US | disclosed |
| WO-2002005800-A9 | COMPOSITIONS FOR SUSTAINED RELEASE OF ANALGESIC AGENTS, AND METHODS OF MAKING AND USING THE SAME | GUILFORD PHARM INC (US) | 2003-08-28 | — | — | WO | disclosed |
| WO-2003060799-A2 | COMPOSITIONS FOR TREATMENT OF CENTRAL NERVOUS SYSTEM NEOPLASMS, AND METHODS OF MAKING AND USING THE SAME | GUILFORD PHARMACEUTICALS, INC. (US) | 2003-07-24 | — | — | WO | disclosed |
| US-20030133903-A1 | Compositions for treatment of prostate cancers and methods of making and using the same | GUILFORD PHARMACEUTICALS, INC. | 2003-07-17 | — | — | US | disclosed |
| US-20030134892-A1 | Compositions for treatment of head and neck cancers, and methods of making and using the same | GUILFORD PHARMACEUTICALS, INC. | 2003-07-17 | — | — | US | disclosed |
| WO-2003007915-A2 | COMPOSITIONS FOR TREATMENT OF HEAD AND NECK CANCERS, AND METHODS OF MAKING AND USING THE SAME | GUILFORD PHARMACEUTICALS, INC. (US) | 2003-01-30 | — | — | WO | disclosed |
| WO-2003007914-A2 | BIOCOMPATIBLE POLYMER CONTAINING COMPOSITION FOR TREATMENT OF PROSTATE CANCERS | GUILFORD PHARMACEUTICALS, INC. (US) | 2003-01-30 | — | — | WO | disclosed |
| US-20020198135-A1 | Compositions for release of radiosensitizers, and methods of making and using the same | JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE | 2002-12-26 | — | — | US | disclosed |
| US-20020141966-A1 | Compositions for treatment of malignant effusions, and methods of making and using the same | GUILFORD PHARMACEUTICALS, INC. | 2002-10-03 | — | — | US | disclosed |
| US-6455665-B1 | ETHYL OR HEXYL DICHLOROPHOSPHATE OR DICHLOROPHOSPHONATE REACTED WITH A POLYESTER PREPOLYMER | GUILFORD PHARMACEUTICALS INC. | 2002-09-24 | — | — | US | disclosed |
| WO-2002040001-A2 | COMPOSITIONS FOR TREATMENT OF MALIGNANT EFFUSIONS COMPRISING A BIOCOMPATIBLE POLYMER AND ANTINEOPLASTIC TAXANE | GUILFORD PHARMACEUTICALS INC. (US) | 2002-05-23 | — | — | WO | disclosed |
| US-20020045668-A1 | Compositions for sustained release of analgesic agents, and methods of making and using the same | GUILFORD PHARMACEUTICALS, INC. | 2002-04-18 | — | — | US | disclosed |
| WO-2002030472-A2 | COMPOSITIONS FOR RELEASE OF RADIOSENSITIZERS, AND METHODS OF MAKING AND USING THE SAME | GUILFORD PHARMACEUTICALS, INC. (US) | 2002-04-18 | — | — | WO | disclosed |
| US-20020041897-A1 | Compositions for sustained release of antineoplastic taxanes, and methods of making and using the same | GUILFORD PHARMACEUTICALS, INC. | 2002-04-11 | — | — | US | disclosed |
| US-20020028911-A1 | Ethyl or hexyl dichlorophosphate or dichlorophosphonate reacted with a polyester prepolymer | EISAI INC. | 2002-03-07 | — | — | US | disclosed |
| WO-2002005800-A2 | COMPOSITIONS FOR SUSTAINED RELEASE OF ANALGESIC AGENTS, AND METHODS OF MAKING AND USING THE SAME | GUILFORD PHARMACEUTICALS, INC. (US) | 2002-01-24 | — | — | WO | disclosed |
| WO-2002003957-A2 | COMPOSITIONS FOR SUSTAINED RELEASE OF ANTINEOPLASTIC TAXANES, AND METHODS OF MAKING AND USING THE SAME | GUILFORD PHARMACEUTICALS, INC. (US) | 2002-01-17 | — | — | WO | disclosed |
| WO-2002004544-A2 | POLYMERS AND POLYMERIZATION PROCESSES | GUILFORD PHARMACEUTICALS (US) | 2002-01-17 | — | — | WO | disclosed |