Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ITGAL | P20701 | 5/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | ITGB2 | P05107 | 4/20 | 0.32 |
| ▸ | ICAM1 | P05362 | 4/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.31 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6199881 | 0.82 | ITGAL (0.46) | ITGALITGB2ICAM1 | |
| SCHEMBL6195996 | 0.80 | ITGAL (0.37) | ALDH1A1ITGALITGB2ICAM1 | |
| SCHEMBL6198868 | 0.80 | ITGAL (0.48) | ITGALITGB2ICAM1 | |
| SCHEMBL6199372 | 0.80 | ITGAL (0.49) | ALDH1A1L3MBTL1KMT2AMEN1ITGAL | |
| SCHEMBL6200570 | 0.79 | MEN1 (0.37) | KMT2AMEN1ITGALITGB2ICAM1 | |
| SCHEMBL6200686 | 0.78 | ITGAL (0.39) | ALDH1A1ITGALITGB2ICAM1 | |
| SCHEMBL6196887 | 0.78 | ITGAL (0.50) | ALDH1A1ITGALITGB2ICAM1 | |
| SCHEMBL6199302 | 0.78 | KMT2A (0.43) | ALDH1A1L3MBTL1KMT2AMEN1ITGAL | |
| SCHEMBL6196674 | 0.77 | ITGAL (0.39) | L3MBTL1ITGALITGB2ICAM1 | |
| SCHEMBL6200015 | 0.77 | MEN1 (0.42) | ALDH1A1L3MBTL1KMT2AMEN1ITGAL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6878700-B1 | Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds | ABBOTT LABORATORIES (US) | 2005-04-12 | — | — | US | claimed |
| US-6878700-B1 | Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds | ABBOTT LABORATORIES (US) | 2005-04-12 | — | — | US | disclosed |
| US-6867203-B2 | Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds | ABBOTT LABORATORIES (US) | 2005-03-15 | — | — | US | disclosed |
| US-20040116518-A1 | Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds | ABBOTT LABORATORIES | 2004-06-17 | — | — | US | disclosed |