Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.49 |
| ▸ | RAB9A | P51151 | 7/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | NPC1 | O15118 | 6/20 | 0.49 |
| ▸ | HPGD | P15428 | 6/20 | 0.49 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | GRM5 | P41594 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | THPO | P40225 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6317950 | 1.00 | SMN1; SMN2 (0.49) | SMN1; SMN2RAB9AKDM4EALDH1A1NPC1 | |
| SCHEMBL9247614 | 0.79 | KMT2A (0.50) | SMN1; SMN2RAB9AKDM4EALDH1A1NPC1 | |
| SCHEMBL28844510 | 0.78 | ERBB2 (0.58) | ERBB2 | |
| SCHEMBL28844508 | 0.78 | ERBB2 (0.58) | ERBB2 | |
| SCHEMBL22398332 | 0.77 | ERBB2 (0.50) | SMN1; SMN2RAB9ANPC1GRM4TDP1 | |
| SCHEMBL14523934 | 0.77 | ERBB2 (0.50) | SMN1; SMN2RAB9ANPC1CYP2C19MAPT | |
| SCHEMBL740909 | 0.75 | NPC1 (0.42) | SMN1; SMN2RAB9AKDM4EALDH1A1NPC1 | |
| SCHEMBL743374 | 0.75 | ELANE (0.44) | SMN1; SMN2RAB9AKDM4EALDH1A1NPC1 | |
| SCHEMBL743228 | 0.75 | ELANE (0.44) | SMN1; SMN2RAB9AKDM4EALDH1A1NPC1 | |
| SCHEMBL740908 | 0.75 | NPC1 (0.42) | SMN1; SMN2RAB9AKDM4EALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6956049-B1 | Methods of modulating processes mediated by excitatory amino acid receptors | MERCK & CO., INC. (US) | 2005-10-18 | — | — | US | disclosed |