⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL176455 | 0.69 | — | — | |
| Water SCHEMBL7203461 | 0.68 | — | — | |
| Bromide SCHEMBL11269881 | 0.68 | — | — | |
| SCHEMBL11884509 | 0.66 | — | — | |
| SCHEMBL10751571 | 0.62 | — | — | |
| SCHEMBL7362965 | 0.61 | — | — | |
| SCHEMBL8136552 | 0.59 | — | — | |
| SCHEMBL10703569 | 0.59 | — | — | |
| SCHEMBL10888769 | 0.55 | — | — | |
| SCHEMBL218833 | 0.49 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0221293-B1 | 7,8,9,10-Tetrahydro-6-oxo-6H-dibenzo[b,d]pyranyloxy-propanes | PENNWALT CORPORATION (US) | 1989-03-08 | — | — | EP | claimed |
| US-20120214798-A1 | Novel Ethanediamone Hepcidine Antagonists | VIFOR (INTERNATIONAL) AG (CH) | 2012-08-23 | — | — | US | disclosed |
| US-6949552-B2 | Remedial agent for anxiety neurosis or depression and piperazine derivative | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2005-09-27 | — | — | US | disclosed |
| US-6861418-B2 | 4-aryl substituted indolinones | SUGEN, INC. (US) | 2005-03-01 | — | — | US | disclosed |
| US-20040157909-A1 | 4-Aryl substituted indolinones | SUGEN, INC. | 2004-08-12 | — | — | US | disclosed |
| US-6677368-B2 | 4-aryl substituted indolinones | SUGEN, INC. | 2004-01-13 | — | — | US | disclosed |
| EP-0147510-B1 | DIBENZOPYRAN DERIVATIVES | FISONS CORPORATION (US) | 1989-08-16 | — | — | EP | disclosed |
| EP-0221293-B1 | 7,8,9,10-Tetrahydro-6-oxo-6H-dibenzo[b,d]pyranyloxy-propanes | PENNWALT CORPORATION (US) | 1989-03-08 | — | — | EP | disclosed |