SCHEMBL6319453

SCHEMBL6319453

Cc1c[nH]c(CCC(c2nc(C)c(O)[nH]2)P2(=O)OCC(C)(C)CO2)n1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6324570 0.76 CYP1A2 (0.31)
SCHEMBL6319853 0.70
SCHEMBL6325825 0.63
SCHEMBL6317930 0.58
SCHEMBL4766858 0.56 CAPN1 (0.40)
SCHEMBL542826 0.56
SCHEMBL13953041 0.55
Water SCHEMBL28791280 0.54 GLA (0.34)
Methane SCHEMBL28186517 0.54 GLA (0.34)
Iodide SCHEMBL633579 0.54 GLA (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050143349-A1 Phosphorus containing compounds useful for the regulation of LDL and Lp(a) levels QUATRX PHARMACEUTICALS CO. 2005-06-30 US claimed
US-20050143349-A1 Phosphorus containing compounds useful for the regulation of LDL and Lp(a) levels QUATRX PHARMACEUTICALS CO. 2005-06-30 US disclosed