Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6204190 | 0.84 | MAPT (0.57) | MAPTRAB9AALDH1A1KMT2AMEN1 | |
| SCHEMBL10418945 | 0.82 | HSP90AA1 (0.48) | MAPTHSP90AA1ALDH1A1KMT2AMEN1 | |
| SCHEMBL11643096 | 0.81 | HSP90AA1 (0.47) | MAPTHSP90AA1RAB9AKMT2AMEN1 | |
| SCHEMBL11641005 | 0.81 | MAPT (0.56) | MAPTHSP90AA1RAB9ARAD52KMT2A | |
| SCHEMBL6319766 | 0.80 | MAPT (0.44) | MAPTHSP90AA1RAB9AALDH1A1KMT2A | |
| SCHEMBL6202608 | 0.77 | MAPT (0.67) | MAPTHSP90AA1RAB9AALDH1A1KDM4E | |
| SCHEMBL10799736 | 0.76 | MAPT (0.49) | MAPTHSP90AA1ALDH1A1KMT2AMEN1 | |
| SCHEMBL6222574 | 0.75 | CYP19A1 (0.49) | MAPTRAB9AKMT2AMEN1CYP19A1 | |
| SCHEMBL1874758 | 0.74 | HSP90AA1 (0.47) | HSP90AA1KMT2ACYP19A1 | |
| SCHEMBL6325976 | 0.74 | CYP1A2 (0.52) | MAPTHSP90AA1ALDH1A1KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050272036-A1 | Ketones | ASTRAZENECA AB (SE) | 2005-12-08 | — | — | US | disclosed |