SCHEMBL6320665

SCHEMBL6320665

O=C(c1ccccc1)c1ccc(OC(CCCOc2ccccc2)C(=O)c2ccccc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.56
PPARA Q07869 4/20 0.56
PPARG P37231 3/20 0.52
PPARD Q03181 1/20 0.52
LMNA P02545 3/20 0.51
L3MBTL1 Q9Y468 3/20 0.51
MAPK1 P28482 1/20 0.51
PARP10 Q53GL7 1/20 0.50
MAPT P10636 3/20 0.49
PKM P14618 1/20 0.49
KDM4E B2RXH2 3/20 0.48
HRH4 Q9H3N8 1/20 0.48
LTA4H P09960 1/20 0.48
ALDH1A1 P00352 2/20 0.47
TDP1 Q9NUW8 1/20 0.45
RAB9A P51151 1/20 0.44
LSS P48449 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10623741 0.81 PPARA (0.51) GAAPPARAPPARGPPARDLMNA
SCHEMBL6319890 0.81 PPARA (0.59) GAAPPARAPPARGPPARDLMNA
SCHEMBL14366324 0.81 GAA (0.77) GAAPPARAPPARGPPARDLMNA
SCHEMBL9634846 0.81 PPARG (0.64) PPARAPPARGPPARDL3MBTL1MAPK1
SCHEMBL11345159 0.79 PPARG (0.70) PPARAPPARGPPARDPARP10TDP1
SCHEMBL4561660 0.79 GAA (0.79) GAAPPARAPPARGPPARDLMNA
SCHEMBL11485988 0.79 PPARA (0.83) GAAPPARAPPARGPPARDLMNA
SCHEMBL12894539 0.79 GAA (0.64) GAAPPARAPPARGPPARDLMNA
SCHEMBL2127341 0.77 PPARA (0.81) GAAPPARALMNAL3MBTL1MAPK1
SCHEMBL2127003 0.77 PPARA (0.81) GAAPPARALMNAL3MBTL1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6852894-B2 Tribenzoyl compounds CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2005-02-08 US disclosed
EP-0981590-B1 PHOTOINITIATORS AND OXYGEN SCAVENGING COMPOSITIONS CHEVRON PHILLIPS CHEMICAL CO (US) 2004-01-28 EP disclosed
US-20030062505-A1 Tribenzoyl compounds CHEVRON PHILLIPS CHEMICAL COMPANY LP 2003-04-03 US disclosed
US-6139770-A COMPRISES A TRIBENZOYL TRIPHENYLBENZENE OR SUBSTITUTED TRIBENZOYL TRIPHENYLBENZENE PHOTOINITIATOR AND A CATALALYST AS OXYGEN SCAVANGER CHEVRON CHEMICAL COMPANY LLC (US) 2000-10-31 US disclosed
EP-0981590-A1 PHOTOINITIATORS AND OXYGEN SCAVENGING COMPOSITIONS Chevron Chemical Company LLC (US) 2000-03-01 EP disclosed
WO-1998051758-A1 PHOTOINITIATORS AND OXYGEN SCAVENGING COMPOSITIONS CHEVRON CHEMICAL COMPANY LLC (US) 1998-11-19 WO disclosed