Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPM1B | O75688 | 4/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.40 |
| ▸ | PPP1CC | P36873 | 3/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL259158 | 0.89 | PPM1B (0.44) | PPM1BPTPN1PPP1CCTSHRLMNA | |
| SCHEMBL13935570 | 0.85 | PPM1B (0.41) | PPM1BPTPN1PPP1CCTSHRLMNA | |
| SCHEMBL13935517 | 0.85 | PPM1B (0.41) | PPM1BPTPN1PPP1CCTSHRLMNA | |
| SCHEMBL28061410 | 0.85 | TBXA2R (0.34) | PPM1BPTPN1PPP1CCTBXA2RFFAR4 | |
| SCHEMBL17170757 | 0.84 | PPM1B (0.44) | PPM1BPTPN1PPP1CCTSHRLMNA | |
| SCHEMBL13410643 | 0.84 | PPM1B (0.41) | PPM1BPTPN1PPP1CCTSHRLMNA | |
| SCHEMBL258736 | 0.84 | PPM1B (0.41) | PPM1BPTPN1PPP1CCTSHRLMNA | |
| SCHEMBL14534626 | 0.84 | PPM1B (0.41) | PPM1BPTPN1PPP1CCTSHRLMNA | |
| SCHEMBL258830 | 0.84 | PPM1B (0.41) | PPM1BPTPN1PPP1CCTSHRLMNA | |
| SCHEMBL13294281 | 0.84 | PPM1B (0.41) | PPM1BPTPN1PPP1CCTSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050185232-A1 | Volume hologram recording photosensitive composition and its use | NIPPON PAINT CO., LTD. (JP) | 2005-08-25 | — | — | US | disclosed |