Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.63 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.52 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17092611 | 1.00 | TSHR (0.63) | TSHRGABRA1GABRB2POLBLMNA | |
| Hydrochloric Acid SCHEMBL9461595 | 0.98 | TSHR (0.61) | TSHRGABRA1GABRB2POLBLMNA | |
| SCHEMBL3678678 | 0.84 | TSHR (0.44) | TSHRLMNAALDH1A1SLC6A4 | |
| SCHEMBL940014 | 0.83 | TSHR (0.53) | TSHRGABRA1GABRB2POLBLMNA | |
| SCHEMBL5934663 | 0.82 | TSHR (0.50) | TSHRGABRA1GABRB2POLBLMNA | |
| Hydrochloric Acid SCHEMBL326013 | 0.82 | TSHR (0.52) | TSHRGABRA1GABRB2POLBLMNA | |
| SCHEMBL5792353 | 0.80 | TSHR (0.50) | TSHRGABRA1GABRB2POLBLMNA | |
| SCHEMBL12610425 | 0.80 | TSHR (0.65) | TSHRGABRA1GABRB2POLBLMNA | |
| SCHEMBL2990957 | 0.80 | TSHR (0.65) | TSHRGABRA1GABRB2POLBLMNA | |
| SCHEMBL9750794 | 0.80 | TSHR (0.48) | TSHRGABRA1GABRB2POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12383515-B2 | Compositions and methods of use of γ-ketoaldehyde scavengers for treating, preventing or improving nonalcoholic fatty liver disease (NAFLD), NASH, ALD or conditions related to the liver | MTI BIOTECH, INC. (US) | 2025-08-12 | — | — | US | claimed |
| CN-119212681-A | Method for preparing 3-D printed pharmaceutical products | 百时美施贵宝公司 | 2024-12-27 | — | — | CN | claimed |
| CN-118290290-A | Preparation method and application of continuous flow for synthesizing ethylsalicylamine | 天津大学 | 2024-07-05 | — | — | CN | claimed |
| CN-117597115-A | Coated solid pharmaceutical preparation | SS制药株式会社 | 2024-02-23 | — | — | CN | claimed |
| CN-122055143-A | Solid compositions containing bromhexine | 第一三共健康事业株式会社 | 2026-05-15 | — | — | CN | disclosed |
| CN-119486761-A | Hyaluronic acid derivative pharmaceutical composition and pharmaceutical composition | 旭化成株式会社 | 2025-02-18 | — | — | CN | disclosed |
| CN-119278035-A | Solid preparation and method for producing the same | 第一三共健康事业株式会社 | 2025-01-07 | — | — | CN | disclosed |
| CN-119212681-A | Method for preparing 3-D printed pharmaceutical products | 百时美施贵宝公司 | 2024-12-27 | — | — | CN | disclosed |
| CN-118660695-A | Pharmaceutical kit for parenteral combination administration | G2G生物公司 | 2024-09-17 | — | — | CN | disclosed |
| CN-118562694-A | Microorganism expressing exogenous protein and use thereof | 丽必微股份有限公司 | 2024-08-30 | — | — | CN | disclosed |
| CN-118512598-A | Aqueous composition containing hypromellose acetate succinate and method for producing solid preparation | 信越化学工业株式会社 | 2024-08-20 | — | — | CN | disclosed |
| CN-118401124-A | Tablet containing lactic acid bacteria | 麒麟控股株式会社 | 2024-07-26 | — | — | CN | disclosed |
| US-5200561-A | PROCESS FOR PRODUCING OPTICALLY ACTIVE AMINES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-04-06 | — | — | US | disclosed |
| EP-0311385-B1 | OPTICALLY ACTIVE HYDROXYBENZYLAMINE DERIVATIVE, OPTICALLY ACTIVE AMINE-BORON COMPOUND CONTAINING SAID DERIVATIVE, AND PROCESS FOR PRODUCING OPTICALLY ACTIVE COMPOUND BY USING SAID COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-02-03 | — | — | EP | disclosed |
| US-5120853-A | Reacting optically active amine-boron complex with oxime or ketone to produce opotically active amine or alcohol compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-06-09 | — | — | US | disclosed |
| EP-0485069-A1 | Process for producing optically active amines | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-05-13 | — | — | EP | disclosed |
| US-5011989-A | Asymmetric reducing agents | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-04-30 | — | — | US | disclosed |
| EP-0311385-A2 | Optically active hydroxybenzylamine derivative, optically active amine-boron compound containing said derivative, and process for producing optically active compound by using said compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1989-04-12 | — | — | EP | disclosed |
| US-4108868-A | 3-(Hydroxyhydrocarbylsecondaryamino)thiophene 1,1-dioxides and polyurethanes chain extended therewith | UNIROYAL, INC. (US) | 1978-08-22 | — | — | US | disclosed |
| US-3983139-A | 3-(Hydroxyhydrocarbylsecondaryamino)thiophene 1,1-dioxides and polyurethanes chain extended therewith | UNIROYAL INC. (US) | 1976-09-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12383515-B2 | Compositions and methods of use of γ-ketoaldehyde scavengers for treating, preventing or improving nonalcoholic fatty liver disease (NAFLD), NASH, ALD or conditions related to the liver | AKR7A2, CPT1A, FABP1 | TSHR 4558/4885GABRA1 2090/4885GABRB2 1064/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.