SCHEMBL6323189

SCHEMBL6323189

O=C(O)CC(C(=O)O)N(C(CC(=O)O)C(=O)O)C(CC(=O)O)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.46
SLC22A6 Q4U2R8 1/20 0.43
FOLH1 Q04609 2/20 0.39
GABRR1 P24046 2/20 0.36
LMNA P02545 1/20 0.36
TSHR P16473 1/20 0.35
ALDH1A1 P00352 1/20 0.32
GAA P10253 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
CPA1 P15085 2/20 0.32
CPB1 P15086 1/20 0.32
CPA3 P15088 1/20 0.32
CPB2 Q96IY4 1/20 0.32
MAPT P10636 1/20 0.32
EPOR P19235 1/20 0.31
KDM4A O75164 1/20 0.31
TET2 Q6N021 1/20 0.31
KDM4C Q9H3R0 1/20 0.31
KDM2A Q9Y2K7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19729271 0.85 TDP1 (0.40) TDP1SMN1; SMN2SLC22A6FOLH1
SCHEMBL6435732 0.85 TDP1 (0.40) TDP1SMN1; SMN2SLC22A6FOLH1
Hydrochloric Acid SCHEMBL6946983 0.83 TDP1 (0.39) TDP1SMN1; SMN2SLC22A6FOLH1
SCHEMBL4998500 0.83 TDP1 (0.39) TDP1SMN1; SMN2SLC22A6FOLH1ALDH1A1
SCHEMBL7777426 0.83 SMN1; SMN2 (0.42) TDP1SMN1; SMN2SLC22A6GABRR1LMNA
SCHEMBL629343 0.83 SMN1; SMN2 (0.42) TDP1SMN1; SMN2SLC22A6GABRR1LMNA
SCHEMBL29650586 0.80 TDP1 (0.46) TDP1SMN1; SMN2SLC22A6FOLH1GABRR1
SCHEMBL31434997 0.80 TDP1 (0.46) TDP1SMN1; SMN2SLC22A6FOLH1GABRR1
SCHEMBL20206 0.80 TDP1 (0.46) TDP1SMN1; SMN2SLC22A6FOLH1GABRR1
SCHEMBL9680512 0.79 SMN1; SMN2 (0.39) TDP1SMN1; SMN2SLC22A6GABRR1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050058619-A1 Polyether-modified polymers as leather auxiliaries LANXESS DEUTSCHLAND GMBH (DE) 2005-03-17 US disclosed
US-20040175661-A1 Granular solid photographic processing agent and production method thereof FUJI PHOTO FILM CO., LTD. (JP) 2004-09-09 US disclosed
EP-1455226-A1 Granular solid photographic processing agent and production method thereof FUJI PHOTO FILM CO., LTD. (JP) 2004-09-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050058619-A1 Polyether-modified polymers as leather auxiliaries PUF60, B2M, CBR3 TDP1 4570/4885SMN1; SMN2 4046/4885SLC22A6 2043/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.